hCD147

品系全名

C57BL/6JSmo-Bsgtm1(hBSG)Smoc

目录号

NM-HU-2000021

品系状态

活体

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基因信息

基因名
Bsg

品系描述

通过同源重组,将小鼠Bsg基因进行人源化修饰。
应用领域:免疫治疗;药物筛选

验证数据

CD147-HU.png

图1 FACS 检测CD147人源化小鼠纯合子红细胞中人源CD147的表达。


发表文献 4篇

1. Inducible CD147 up-regulation boosts extended SARS-CoV-2 infection triggering severe COVID-19 independent of ACE2
发表年份:2026 来源杂志:Signal Transduction and Targeted Therapy

2. CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis
发表年份:2022 来源杂志:Signal Transduction and Targeted Therapy

3. CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma
发表年份:2021 来源杂志:Signal Transduction and Targeted Therapy

4. CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells
发表年份:2020 来源杂志:Signal Transduction and Targeted Therapy

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