hIL15-Tg(M-NSG)

品系全名

NOD.Cg-PrkdcscidIl2rgem1Tg(hIL15)Smoc

目录号

NM-KI-210141

品系状态

胚胎冻存

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基因信息

基因名
Il15

品系描述

利用转基因技术将人源IL15基因表达框整合到小鼠基因组中,从而表达人源IL15。

验证数据

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Fig1. Human IL15 expression analysis in hIL15-Tg(N-NSG) mice by ELISA.

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Fig2. Body weight of hIL15-Tg(M-NSG) post inoculation. 

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Fig3. Humanized immune reconstitution levels in hIL15-Tg(M-NSG) mice engrafted with human HSC.

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Fig4. hIL15-Tg(M-NSG) mice engrafted with human HSCs exhibit high expression of functional proteins such as NKG2D, Granzyme B, and NKp46.


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