hPD-L1/hLAG3
品系全名
C57BL/6JSmo-Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc
目录号
NM-HU-00137
品系状态
胚胎冻存
品系描述
验证数据
图1 FACS检测PD-L1/LAG3双人源化小鼠CD3+T细胞中人源PD-L1&LAG3的表达。结果显示：PD-L1/LAG3双人源化纯合子小鼠通过尾静脉注射刀豆蛋白（12mg/kg）刺激18h，取脾脏细胞进行流式验证。 PD-L1/LAG3人源化纯合子小鼠脾脏的CD3+T细胞中人源PD-L1和LAG3都表达活跃，且都无鼠源PD-L1和LAG3表达。
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