hVSIG4

Fig1. Analysis of human VSIG4 expression on the peritoneal exudate macrophages by FACS. 

The homozygous KI mouse expresses human VSIG4 on the peritoneal exudate macrophages.

Fig.2 In vivo efficacy assessment of anti-hVSIG4 in HO hVSIG4 mice bearing MC38 syngeneic tumor.

Body weight were measured twice a week of hVSIG4 mice (n=4 , 3 male and 1 female). (A) Body weight. (B) Body weight change.

Fig.3 In vivo efficacy assessment of anti-hVSIG4 in HO hVSIG4 mice bearing MC38 syngeneic tumor.

Tumor volume were measured twice a week of hVSIG4 mice. MC38 (1×10⁶) were inoculated subcutaneously into hVSIG4 mice (6-8-week-old, n=4, 3 male and 1 female). (A) Tumor volume. (B) Relative tumor volume.