hIL1B(BALB/c)

品系全名

BALB/cJSmo-Il1btm3(hIL1B)Smoc

目录号

NM-HU-220017

品系状态

胚胎冻存

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基因信息

基因名
IL1B

品系描述

通过同源重组,将小鼠Il1b基因进行人源化修饰。

验证数据

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Fig1. Detection of IL-1B expression in spleen and lung by RT-PCR. Wild type: only one band at 209 bp with primers F1/R1(mIl-1b);Heterozygous: one band at 209 bp with primers F1/R1(mIl-1b) and one band at 291 bp with primers F2/R2(hIL-1B); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig 2. Detection of hIL1B expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hIL1B and Balb/c mice were i.p. injected with LPS(10mg/kg) for 6h.


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