hIL5/hIL5R(2)

品系全名

C57BL/6JSmo-Il5tm3(hIL5)Il5ratm2(hIL5RA)Smoc

目录号

NM-HU-220010

品系状态

精子冻存

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品系描述

通过同源重组,将小鼠Il5基因和IL5R进行人源化修饰。与此相似的品系还有hIL5/hIL5R(NM-HU-2000101)和hIL5/hIL5R(NM-HU-220011),详细信息请咨询技术顾问。
应用领域:免疫治疗;肿瘤研究;药物筛选

验证数据

image.png

Fig1. Expression of hIL5R on Bone marrow-derived eosinophils in hIL5/hIL5R(2) KI mice.

Note: Eosinophils were derived from bone marrow cells through culture with rmSCF, rmFLT-3L, and rmlL-5.



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