hGPRC5D

品系全名

C57BL/6JSmo-Gprc5dtm1(hGPRC5D)Smoc

目录号

NM-HU-215058

品系状态

活体

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基因信息

基因名
Gprc5d

品系描述

利用同源重组,将小鼠Gprc5d基因进行人源化修饰。

验证数据

image.png

Fig.1 Detection of GPRC5D expression in mammary gland and liver of 9-week-old female WT and hGPRC5D mice by RT-PCR. 

Wild type: only one band at 253 bp with primers F1/R1(mGprc5d);

Homozygous:  only one band at 409 bp with primers F2/R2(hGPRC5D).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human GPRC5D expression in 9-week-old female WT and hGPRC5D knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

Note. The anti-human GPRC5D antibody cross-reacted with mouse GPRC5D and humanized GPRC5D.


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