pAlb-hLPA-Tg

品系全名

C57BL/6JSmo-Tg(pAlb-hLPA)1Smoc

目录号

NM-TG-225001

品系状态

活体

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品系描述

通过随机转基因方式,将pAlb-hLPA整合到小鼠染色体。
应用领域:核酸药物人源化

验证数据

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Fig.1 Detection of hLPA expression in serum by ELISA (n=15). 

Abbr. WT, wild type.

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Fig.2 Detection of hLPA expression in serum by ELISA (male, n=5). 

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Fig.3 Detection of serum LPa protein level (A) and liver mRNA remaining (B) after single dose of positive control compound (n=2/group). (Data from a collaborator)

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Fig.4 Detection of serum LPa protein level (A) and liver mRNA remaining (B) after single dose of test compounds (n=4/group). (Data from a collaborator)


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