hKLRG1(3)

利用同源重组，将小鼠Klrg1基因进行人源化修饰。

Fig.1 Detection of KLRG1 expression in spleen by RT-PCR. 

Wild type: only one band at 194 bp with primers F1/R1(mKlrg1);

Homozygous: only one band at 185 bp with primers F2/R2(hKLRG1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

Fig.2 Detection of mKLRG1 expression on NK cells and T cells in peripheral blood. (male, 9 weeks old)

Fig.3 Detection of hKLRG1 expression on NK cells and T cells in peripheral blood. (male, 9 weeks old)

Fig.4 Detection of mKLRG1 expression on NK cells and T cells in Spleen. (male, 9 weeks old)

Fig.5 Detection of hKLRG1 expression on NK cells and T cells in Spleen. (male, 9 weeks old)