hIL22
品系全名
C57BL/6Smoc-Il22em(hIL22)Smoc
目录号
NM-HU-220419
品系状态
胚胎冻存
基因信息
基因名
Il22
品系描述
利用同源重组，将小鼠Il22 基因进行人源化修饰。该品系上架销售日期为2026年2月25日。
*使用本品系发表的文献需注明: hIL22 mice (Cat. NO. NM-HU-220419) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of IL22 expression in cerebellum by RT-PCR.
Wild type: only one band at 486 bp with primers F1/R1(mIl22);
Homozygous: only one band at 356 bp with primers F2/R2(hIL22).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig. 2 Detection of human IL22 expression(A) and mouse IL22(B) in serum by ELISA. (n=3 for both groups )
Abbr. HO, homozygous; WT, wild type; N.D. not detected.
Note. The hIL22 and C57BL/6 mice were i.p. injected with LPS for 6h. The mouse IL22 ELISA kit cross-reacted with mIL22 and humanized IL22.
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