Neto1-Cre

品系全名

C57BL/6JSmo-Neto1em1(iCre-pA)Smoc

目录号

NM-KI-200112

品系状态

胚胎冻存

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基因信息

基因名
Neto1

品系描述

将iCre-pA插入到小鼠Neto1基因起始密码子处。
应用领域:Cre工具鼠,2型双极细胞(BC2S),以及一些无长突细胞和视网膜神经节细胞(RGCs)等区域

验证数据

Neto1-(iCre)-1.png


Figure 1: Neto1iCre/+; Rosa26tdTomato/+ 小鼠视网膜中tdTomato表达情况。

Neto1iCre/+; Rosa26tdTomato/+ 双转基因鼠,可在视网膜双极细胞中表达tdTomato。证明Neto1-(iCre)小鼠可以成为实现Neto1阳性细胞特异性敲除或表达的工具鼠。

Neto1-(iCre)-2.png

Figure 2: Neto1iCre/+; Rosa26tdTomato/+ 小鼠各组织中tdTomato的表达情况。


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