Sst-IRES-Cre

品系全名

C57BL/6JSmo-Sst1em1(IRES-Cre-Wpre-polyA)Smoc

目录号

NM-KI-190091

品系状态

活体

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基因信息

基因名
Sst

品系描述

将IRES-Cre-Wpre-polyA共表达结构插入到小鼠Sst基因终止密码子处。
应用领域:Cre工具鼠,生长抑素表达神经元,可能被用于研究树突抑制神经元。

验证数据

sst-cre-1.png

图 1荧光检测Sst-Cre+/-; Rosa26 tdTomato+/- 小鼠小脑神经元tdTomato的表达。

结果显示:双阳性小鼠小脑神经元有tdTomato的表达,表达类型符合预期。

sst-cre-2.png

图 2荧光检测Sst-Cre+/-; Rosa26 tdTomato+/- 小鼠大脑、胼胝体和间脑神经元tdTomato的表达。

结果显示:双阳性小鼠大脑、胼胝体和间脑神经元有tdTomato的表达,表达类型符合预期。

sst-cre-3.png

图 3荧光检测Sst-Cre+/-; Rosa26 tdTomato+/- 小鼠大脑和嗅球神经元tdTomato的表达。

结果显示:双阳性小鼠大脑和嗅球神经元有tdTomato的表达,表达类型符合预期。


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