Fgfbp1-2A-EGFP-2A-CreERT2
品系全名
C57BL/6Smoc-Fgfbp1em1(P2A-EGFP-T2A-CreERT2)Smoc
目录号
NM-KI-241684
品系状态
精子冻存
基因信息
基因名
Fgfbp1
品系描述
将P2A-EGFP-T2A-CreERT2插入到小鼠Fgfbp1基因终止密码子处。
*使用本品系发表的文献需注明: Fgfbp1-2A-EGFP-2A-CreERT2 mice (Cat. NO. NM-KI-241684) were purchased from Shanghai Model Organisms Center, Inc..
鉴定报告
下载验证数据
Fig1. CreERT2 mediated recombination in small intestine of Fgfbp12A-EGFP-2A-CreERT2/+; Rosa26tdTomato/+ mouse.
Fig2. Detection of tdTomato(red) and EGFP(Green) in various tissues of Fgfbp12A-EGFP-2A-CreERT2/+; Rosa26tdTomato/+ mouse.
Tissues expressing tdTomato after tamoxifen induction include: colon, lung, small intestine, skin, stomach.
In the control group, non-specific expression was observed in the small intestine. (89-days old, female and male) (For more detailed information please contact our technical advisor.)
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Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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