Tg-2A-CreERT2

品系全名

C57BL/6JSmo-Tgem1(2A-CreERT2-WPRE-polyA)Smoc

目录号

NM-KI-215040

品系状态

精子冻存

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基因信息

基因名
Tg

品系描述

将2A-CreERT2-WPRE-polyA插入到小鼠Tg基因终止密码子处。CreERT2有泄露情况,请根据研究目的使用该品系。

验证数据

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Fig1. Cre mediated recombination in thyroid of TgCreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig2. Detection of tdTomato(red) in various tissues of TgCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: thyroid gland and salivary gland. A few cells expressed in lung, liver, adrenal gland, kidney, colon, small intestine, spleen, ovary, thymus and pituitary gland. Tissues that unexpressed include brain, spinal cord, retina, heart, stomach, brown fat, pancreas, muscle, epidermis.Thyroid is expressed before induction.(4-weeks old, male) (For more detailed information please contact our technical advisor.) 


发表文献 1篇

1. Kynurenine acts as a signaling molecule to attenuate pulmonary fibrosis by enhancing the AHR-PTEN axis
发表年份:2024 来源杂志:Journal of Advanced Research

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