Cyp4v3-KO

品系全名

C57BL/6JSmo-Cyp4v3em1Smoc

目录号

NM-KO-200711

品系状态

胚胎冻存

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基因信息

基因名
Cyp4v3

品系描述

敲除Cyp4v3基因exon 2-6,建立Cyp4v3基因敲除小鼠模型。

疾病预测

Bietti结晶性角膜视网膜营养不良
Bietti Crystalline Corneoretinal Dystrophy

验证数据

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Fig.1 Detection of Cyp4v3 expression in the liver by qPCR. 

Total RNA was extracted from wild-type C57BL/6J mice (WT) and homozygous Cyp4v3-KO mice (HO), which have been put on a high fat-diet for 49-50 weeks (male, 53-54 weeks old), then cDNA libraries were synthesized by reverse transcription, followed by qPCR with mouse Cyp4v3 and Gapdh primers. Relative expression represents Cyp4v3 mRNA levels relative to its average expression in WT mice.


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