Th-2A-tdTomato

品系全名

C57BL/6Smoc-Them1(2A-tdTomato)Smoc

目录号

NM-KI-210124

品系状态

活体

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基因信息

基因名
Th

基因曾用名

-

染色体位置

7

NCBI ID

21823

MGI ID

98735

Ensembl ID

ENSMUSG00000000214

Pubmed

Th

人类同源基因

TH

品系描述

将2A-tdTomato插入到小鼠Th基因终止密码子。
应用领域：该小鼠在Th基因座表达报告基因( tdTomato)。该报告基因在儿茶酚胺能细胞中表达，可用于研究多巴胺能细胞功能、帕金森病和其他神经退行性疾病。

验证数据

NM-KI-210124 Th-2A-tdTomato-1.png

图 1  在ThtdTomato/+ 小鼠脑部，tdTomato的表达情况。

ThtdTomato/+ 小鼠，可在小鼠嗅球(olfactory bulb, OB)和腹侧被盖区(ventral tegmental area, VTA)中表达tdTomato。

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