Abcb1a/Abcb1b-KO(FVB)

品系全名

FVB-Abcb1aem1Abcb1bem1Smoc

目录号

NM-KO-191211

品系状态

活体

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品系描述

通过CRISPR基因编辑技术,将Abcb1a和Abcb1b基因进行敲除(敲除区域从Abcb1a基因exon2到Abcb1b基因exon28)。

验证数据

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Fig1. In vivo PK profiles of Digoxin in FVB and Abcb1a/Abcb1b-KO mice (male, 6-8 weeks, n=6)




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