Hc-KO

品系全名

C57BL/6JSmo-Hcem1Smoc

目录号

NM-KO-190191

品系状态

活体

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基因信息

基因名
Hc

品系描述

敲除Hc基因的exon 6 区域,获得Hc基因敲除小鼠模型。
应用领域:免疫相关

验证数据

image.png

Fig.1 Detection of Hc expression in liver by RT-PCR. 

Wild type: one band at 201 bp with primers F1/R1(mHc) and one band at 123 bp with primers F/R(mGapdh);

Hc-KO(HO): only one band at 123 bp with primers F/R(mGapdh). 

Abbr. M, DNA marker;  HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of mC5(A) and mC5a(B) expression in serum by ELISA.

Abbr. WT, wild type; HO, homozygous; N.D. not detected.


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