C57BL/6

品系全名

C57BL/6

目录号

SM-001

品系状态

活体

导出PDF

品系描述

是第一个完成基因组测序的小鼠品系,毛色为黑色,被认作"标准"的近交系,为许多突变基因提供遗传背景。具有品系稳定、易于繁殖,应激反应均一,试验结果精度高等特点。

验证数据

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图1.C57BL/6小鼠生长曲线(n=840)。

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图2.C57BL/6小鼠血常规检测。



发表文献 321篇

1. Cochlear nucleus spatial transcriptomes of normal and hearing loss mice reveal a critical role of Spp1 in bushy cells
发表年份:2026 来源杂志:CELL RESEARCH

2. Machine-Learning-Assisted Triple-Gated Raman Enhancement Platform for Selectively Quantifying Lysophosphatidylcholine (16:0) as a Potential Biomarker for Cognitive Impairments
发表年份:2026 来源杂志:ACS Nano

3. Spatially Defined DNA Origami Cell Engagers for T and Natural Killer Cell-Mediated Immune Modulation
发表年份:2026 来源杂志:ACS Nano

4. Simultaneous dual-Raman-shift scanning-free stimulated Raman scattering microscopy for label-free biomolecular imaging
发表年份:2026 来源杂志:Nature Communications

5. Gut microbial histamine and serotonin promote cerebrovascular angiogenesis: Evidence from moyamoya disease
发表年份:2026 来源杂志:Genes & Diseases

6. Mechanism-Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
发表年份:2026 来源杂志:Advanced Science

7. Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis
发表年份:2026 来源杂志:Science Advances

8. A novel whole cancer cell vaccine based on modified β-glucan elicits robust anti-tumor immunity
发表年份:2026 来源杂志:Theranostics

9. 3D-cultured hUC-MSC-derived exosomes as macrophage mediators to suppress cholestatic fibrosis in mice via miR-1291–mediated multi-targeted pathways
发表年份:2026 来源杂志:CHEMICAL ENGINEERING JOURNAL

10. Unveiling a macrophage-driven inflammatory dysregulation: NF-κB-mediated hyperinflammation links 6PPD-Q exposure to viral immunopathology
发表年份:2026 来源杂志:JOURNAL OF HAZARDOUS MATERIALS

11. Iron-Rich Particles Drive Pulmonary Toxicity of Coal Combustion-Derived Fine Particles via Transferrin Receptor-Mediated Ferroptosis
发表年份:2026 来源杂志:ENVIRONMENTAL SCIENCE & TECHNOLOGY

12. Polystyrene Microplastics Disrupt the Blood-Testis Barrier via CEBPB-Driven Lysosomal Autophagy and Induce Ferroptosis-like Injury in Human Sperm, Compromising Embryo Development
发表年份:2026 来源杂志:JOURNAL OF HAZARDOUS MATERIALS

13. Targeting senescent EGR1+ B cells enhances immunotherapy efficacy in esophageal squamous cell carcinoma
发表年份:2026 来源杂志:Cell Reports Medicine

14. CXCL16-driven CD4+ T cells orchestrate immunosurveillance against MHC-I-deficient hepatocellular tumors
发表年份:2026 来源杂志:Journal for ImmunoTherapy of Cancer

15. Ultrasound-triggered dissolving microneedle platform for cGAS-STING-mediated precision immunotherapy of melanoma
发表年份:2026 来源杂志:Materials Today Bio

16. Ganoderma lucidum polysaccharide ameliorates cancer cachexia with enhanced efficacy in aged group by reprogramming arginine metabolism to modulate Treg formation
发表年份:2026 来源杂志:CANCER LETTERS

17. Programmable Assembly of Artificial Antigen-Presenting Cells with Framework Nucleic Acids
发表年份:2026 来源杂志:NANO LETTERS

18. Post-traumatic stress disorder impairs CD8+ T cell-dependent anti-tumor immune responses by downregulating thiamine
发表年份:2026 来源杂志:Cell Communication and Signaling

19. Long-term sucralose exposure accelerates ovarian aging via gut microbiota dysbiosis
发表年份:2026 来源杂志:npj Science of Food

20. Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells
发表年份:2026 来源杂志:Cell Chemical Biology

21. Glioma Cell Membrane–Coated CaCO3 Nanoparticles for Localized Postoperative Chemo–Calcium Overload Therapy to Prevent Glioma Recurrence
发表年份:2026 来源杂志:International Journal of Nanomedicine

22. Exposure to paraben in early gestational period: Impact on placental estrogen biosynthesis and fetal growth restriction
发表年份:2026 来源杂志:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

23. NOTCH3 attenuates cytotoxicity via RBPJ-dependent PVR upregulation to influence immunotherapy outcomes in colorectal cancer
发表年份:2026 来源杂志:Frontiers in Immunology

24. Botulinum Neurotoxin Type A1 Alleviates Bleomycin-induced Skin Fibrosis by Inhibiting PI3K-Akt Pathway and Associated Cell Cycle and Proliferation
发表年份:2026 来源杂志:JOURNAL OF INVESTIGATIVE DERMATOLOGY

25. Cucurbitacin B attenuates bleomycin-induced pulmonary fibrosis by inhibiting M2 macrophage polarization via PI3K/AKT/mTOR signaling
发表年份:2026 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

26. Eupalinolide B ameliorates liver fibrosis by targeting PKCα to suppress the AKT/mTOR axis in hepatic stellate cells
发表年份:2026 来源杂志:JOURNAL OF ETHNOPHARMACOLOGY

27. Curcumin Targets Crispld2 to Suppress Hepatic Stellate Cell Activation via PI3K/AKT Pathway Inhibition in Hepatic Fibrosis
发表年份:2026 来源杂志:LIVER INTERNATIONAL

28. GABA induces myokine irisin release from skeletal muscle
发表年份:2026 来源杂志:LIFE SCIENCES

29. Palmitoylation Induced Activation of SMAD3 Exacerbates Colitis by Promoting Tissue-resident Memory T Cells Differentiation
发表年份:2026 来源杂志:INFLAMMATION

30. Rapid generation of dental pulp stem cell-derived mineralized extracellular matrix for quantitative osteoclast resorption assays
发表年份:2026 来源杂志:Frontiers in Bioengineering and Biotechnology

31. ROS-responsive diselenide exosomes restores mitophagy to resolve sterile inflammation in liver IRI
发表年份:2026 来源杂志:EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

32. Pedunculoside ameliorates liver fibrosis by targeting c-Jun to inhibit hepatic stellate cell activation
发表年份:2026 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

33. ACSL4 Inhibition by AS-252424 Protects Visual Function by Suppressing RGC Ferroptosis After Retinal Ischemia Reperfusion Injury
发表年份:2026 来源杂志:MOLECULAR NEUROBIOLOGY

34. Polyethylene Microplastic Exposure Disrupts Sex and Gut Hormones via Gut Microbial and Metabolic Pathways
发表年份:2026 来源杂志:FASEB JOURNAL

35. Sex specific modulation of LC neuronal activity in a binge drinking mouse model
发表年份:2026 来源杂志:PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

36. Transcriptional Heterogeneity of Cardiac Remodeling Between Type 1 and Type 2 Diabetes
发表年份:2026 来源杂志:Biomedicines

37. Omega-3 fatty acids improve lipid metabolism by regulating miR-34a
发表年份:2026 来源杂志:Scientific Reports

38. TAF1 Suppresses MHC-I Expression and Correlates with Poor Immunotherapy Response in Small Cell Lung Cancer
发表年份:2026 来源杂志:Biomedicines

39. Lycium barbarum Polysaccharide Alleviates Renal Damage in Mouse Sepsis by Regulating M1/M2 Macrophage Polarization
发表年份:2026 来源杂志:Food Science & Nutrition

40. Vitamin B6 Ameliorates Lipopolysaccharide-Induced Inflammation in Mouse Gastric Organoids
发表年份:2026 来源杂志:CELL BIOLOGY INTERNATIONAL

41. A novel mouse model simulating C5 palsy after cervical surgery
发表年份:2026 来源杂志:Animal Models and Experimental Medicine

42. ELF3/miR-9-5p/NFKB1 axis promotes the progression of osteoarthritis by triggering NLRP3-mediated cell pyroptosis
发表年份:2026 来源杂志:IMMUNOLOGIC RESEARCH

43. Phenothiazine alleviates cisplatin-mediated acute kidney injury by inhibiting ferroptosis
发表年份:2026 来源杂志:CELL AND TISSUE RESEARCH

44. Targeting DNA fragment extrusion: a new therapeutic avenue for CCl4-induced hepatic injury
发表年份:2026 来源杂志:MOLECULAR BIOLOGY REPORTS

45. An Automated Segmentation and Biometry Method for Mouse Axial OCT Images Based on Longitudinal Intensity Profile Analysis (LIPA) in Mouse
发表年份:2026 来源杂志:EXPERIMENTAL EYE RESEARCH

46. Loss of hepaCAM inhibits cholesterol biosynthesis and impairs learning and memory in mice
发表年份:2026 来源杂志:BRAIN RESEARCH

47. Isolation, Identification and Pathogenicity Analysis of Proteus mirabilis in Cynomolgus Monkey From Yunnan, China
发表年份:2026 来源杂志:Veterinary Medicine and Science

48. Pyruvate kinase M2 -mediated histone lactylation alters three-dimensional genomic architecture in polycystic ovary syndrome
发表年份:2025 来源杂志:Signal Transduction and Targeted Therapy

49. Engineering STING Nanoadjuvants for spatiotemporally-tailored innate immunity stimulation and cancer vaccination therapy
发表年份:2025 来源杂志:Nature Communications

50. Combinatorial tagging generates a multi-purpose knock-in mouse model revealing phase separation-dependent germ granules in RNA homeostasis and germline development
发表年份:2025 来源杂志:CELL DEATH AND DIFFERENTIATION

51. Suppression of epileptic seizures by transcranial activation of K+-selective channelrhodopsin
发表年份:2025 来源杂志:Nature Communications

52. Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice
发表年份:2025 来源杂志:Nature Communications

53. Metal-Catalyzed Abiotic Cleavage of C═C Bonds for Effective Fluorescence Imaging of Cu(II) and Fe(III) in Living Systems
发表年份:2025 来源杂志:Advanced Science

54. Inhibiting Liver-Derived C3 Protein Rescues Anesthesia/Surgery-Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis
发表年份:2025 来源杂志:Advanced Science

55. High-Resolution Multiplexed Sequencing of Single-Cell Full-length Transcriptome Via Combinational Barcoded Tn5 Transposon Insertion
发表年份:2025 来源杂志:Advanced Science

56. SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway
发表年份:2025 来源杂志:Advanced Science

57. Reversible acetylation of ribosomal protein S1 serves as a smart switch for Salmonella to rapidly adapt to host stress
发表年份:2025 来源杂志:NUCLEIC ACIDS RESEARCH

58. Glycyrrhiza polysaccharide-adjuvanted liposomal vaccine potentiates tumor immunotherapy through lymph node-targeted modulation of the DC-T cell axis
发表年份:2025 来源杂志:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

59. Sustained mTORC1 activation in activated T cells impairs vaccine responses in older individuals
发表年份:2025 来源杂志:Science Advances

60. Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma
发表年份:2025 来源杂志:ALLERGY

61. Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy
发表年份:2025 来源杂志:JOURNAL OF CONTROLLED RELEASE

62. Gut‐derived bacterial vesicles carrying lipopolysaccharide promote microglia‐mediated synaptic pruning
发表年份:2025 来源杂志:Alzheimers & Dementia

63. ATP11B Modulates Microglial Lipid Metabolism and Alleviates Alzheimer's Disease Pathology
发表年份:2025 来源杂志:MedComm

64. DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma
发表年份:2025 来源杂志:DEVELOPMENTAL CELL

65. Targeting the ac4C ‘Writer’ NAT10 enhances pancreatic cancer immunotherapy via dual modulation of CD8+ T cells and tumor cells
发表年份:2025 来源杂志:Cell Death & Disease

66. Zn-Based Multi-Active Framework Nanoparticles TSA-CAN-Zn Inhibit Skin Glycation via Dual Blockade of HMGB1/RAGE and AGEs/RAGE Pathways
发表年份:2025 来源杂志:Advanced Healthcare Materials

67. Extracellular vesicles for delivery of functional telomerase
发表年份:2025 来源杂志:Cell Communication and Signaling

68. AXL and MERTK facilitate tissue repair in severe acute pancreatitis via a CCR5-dependent neutrophil and macrophage crosstalk
发表年份:2025 来源杂志:Cell Communication and Signaling

69. Bupleuri Radix polysaccharides enhance the efficacy and intestinal absorption of baicalin via regulating intestinal β-glucuronidase activity in MASH mice
发表年份:2025 来源杂志:PHYTOMEDICINE

70. NRF2 modulates WNT signaling pathway to enhance photodynamic therapy resistance in oral leukoplakia
发表年份:2025 来源杂志:EMBO Molecular Medicine

71. An injectable cisplatin hydrogel effectively suppresses tumors while preserving anti-infective immunity
发表年份:2025 来源杂志:MATERIALS & DESIGN

72. The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue
发表年份:2025 来源杂志:npj Science of Food

73. LGR6 modulates intervertebral disc degeneration through regulation of macrophage efferocytosis
发表年份:2025 来源杂志:Journal of Translational Medicine

74. A traditional herbal decoction regulates skeletal muscle satellite cell osteogenesis and myogenesis for repairing osteosarcopenic fractures via β-catenin
发表年份:2025 来源杂志:Stem Cell Research & Therapy

75. Inhibition of epigenetic regulator UHRF1 attenuates renal fibrosis and retains transcription factor Krüppel-like factor 15 expression
发表年份:2025 来源杂志:Cell Death Discovery

76. Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis
发表年份:2025 来源杂志:Cell Reports

77. Activated T cells degrade extracellular proteins to enhance effector functions
发表年份:2025 来源杂志:Cell Reports

78. LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia
发表年份:2025 来源杂志:Cell Reports

79. Optimizing anti-PD-1/PD-L1 therapy efficacy and fecal microbiota transplantation donor selection through gut mycobiome-based enterotype
发表年份:2025 来源杂志:Cell Reports

80. Pseudouridine synthase 1-targeted therapy activates antiviral immunity to boost cancer immunotherapy
发表年份:2025 来源杂志:Cell Reports

81. Neuronal DJ-1 regulates microglial activation in Parkinson’s disease
发表年份:2025 来源杂志:Neural Regeneration Research

82. Low-level expression of Cmyc in mature neurons: maintaining neuronal function and preventing neurodegeneration
发表年份:2025 来源杂志:Neural Regeneration Research

83. Urokinase-loaded Pt Quantum Dot Self-assembly Nanoparticle for Inflammation Elimination and Fibrinolytic Thrombus Therapy
发表年份:2025 来源杂志:Materials Chemistry Frontiers

84. Rhein alleviates hepatic steatosis in NAFLD mice by activating the AMPK/ACC/SREBP1 pathway to enhance lipid metabolism
发表年份:2025 来源杂志:MOLECULAR MEDICINE

85. Camel-Milk-Derived Extracellular Vesicles Mitigate High-Fat-Diet-Induced Obesity by Enhancing Thermogenesis and Modulating Lipid Metabolism in Mice
发表年份:2025 来源杂志:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

86. Kin17 promotes rDNA transcription, ribosomal biogenesis, and cortical lamination
发表年份:2025 来源杂志:EMBO REPORTS

87. USP13 promotes hepatic stellate cells activation and aggravates liver fibrosis through deubiquitinating SMAD3
发表年份:2025 来源杂志:Hepatology International

88. Air pollutants and adverse pregnancy outcomes: A multi-method integration of Mendelian randomization, meta-analysis, and animal models
发表年份:2025 来源杂志:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

89. Moxibustion regulates KDM4D expression and modulates lipid metabolism to inhibit tumor proliferation in CAC mice
发表年份:2025 来源杂志:Cancer Cell International

90. The SDF-1α/MTDH axis inhibits ferroptosis and promotes the formation of anti-VEGF-resistant choroidal neovascularization by facilitating the nuclear translocation of SREBP1
发表年份:2025 来源杂志:CELL BIOLOGY AND TOXICOLOGY

91. Curcumin targets YAP1 to enhance mitochondrial function and autophagy, protecting against UVB-induced photodamage
发表年份:2025 来源杂志:Frontiers in Immunology

92. Kurarinone ameliorates intestinal mucosal inflammation via regulating T cell immunity
发表年份:2025 来源杂志:Frontiers in Immunology

93. Influence of programmed death ligand 1 (PD-L1) knockout on gut microbiota in experimental autoimmune uveitis
发表年份:2025 来源杂志:Frontiers in Immunology

94. Therapeutic efficacy of Sanhuang Xiexin decoction on atopic dermatitis via suppressing STAT3 signaling
发表年份:2025 来源杂志:JOURNAL OF ETHNOPHARMACOLOGY

95. Huang-qin Decoction alleviates Deoxycholic Acid-induced Colorectal Cancer in Mice by Regulating Gut Microbiota
发表年份:2025 来源杂志:JOURNAL OF ETHNOPHARMACOLOGY

96. Translocator protein facilitates neutrophil-mediated mucosal inflammation in inflammatory bowel diseases
发表年份:2025 来源杂志:WORLD JOURNAL OF GASTROENTEROLOGY

97. Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess
发表年份:2025 来源杂志:Biology of Sex Differences

98. High-fat diet induces pre-eclampsia through dampening cell-autonomous C3 in trophoblasts
发表年份:2025 来源杂志:Communications Biology

99. Mechanisms and reversibility of nicotine-induced spermatogenesis impairment and DNA methylation changes
发表年份:2025 来源杂志:Communications Biology

100. Integrated Multiomics Analyses Reveal Molecular Insights into How Intermittent Fasting Ameliorates Obesity and Increases Fertility in Male Mice
发表年份:2025 来源杂志:Nutrients

101. Therapeutic Efficacy and Mechanistic Insights of Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in Chemotherapy-Induced Oral Mucositis
发表年份:2025 来源杂志:JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

102. α-Klotho Supplementation Mitigates Cumulative Exercise-Induced Fatigue via Coordinated NRF2-Mediated Antioxidant Defense and AKT/GS-Driven Hepatic Glycogen Supercompensation in Mice
发表年份:2025 来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

103. Epigenetic Regulation of Ferroptosis by the KDM3A/BRPF1 Transcriptional Axis Confers Neuroprotection in Postpartum Depression mouse model
发表年份:2025 来源杂志:JOURNAL OF AFFECTIVE DISORDERS

104. Exercise ameliorates hepatic lipid accumulation via upregulating serum PRL and activating hepatic PRLR-mediated JAK2/STAT5 signaling pathway in NAFLD mice
发表年份:2025 来源杂志:Frontiers in Pharmacology

105. Integrating global burden of disease analysis and single-cell omics identifies ANTXR2 as a potential diagnostic biomarker for AML in China
发表年份:2025 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

106. Discovery and synthesis of azepinoindoles as novel hCYP1B1 inhibitors with AhR-independent anticancer activity
发表年份:2025 来源杂志:BIOORGANIC CHEMISTRY

107. Tigecycline modulates LPS-induced inflammatory response in sepsis via NF-κB signalling pathways: Experimental insights into immune regulation
发表年份:2025 来源杂志:INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

108. MicroRNA-122-5p is upregulated in diabetic foot ulcers and decelerates the transition from the inflammatory to the proliferative stage
发表年份:2025 来源杂志:World Journal of Diabetes

109. Development of ultrasound-visualized tumor-targeting engineered bacteria for precise tumor therapy
发表年份:2025 来源杂志:Synthetic and Systems Biotechnology

110. Overexpression of thioredoxin 1 contributes to neuroprotection through ATM activation and pentose phosphate pathway modulation after traumatic brain injury
发表年份:2025 来源杂志:EXPERIMENTAL NEUROLOGY

111. Andrographolide inhibits the upregulation of SLC19A3 to block the adipogenic differentiation of adipose-derived stem cells
发表年份:2025 来源杂志:iScience

112. Optimization of thrombopoietin mimetic peptide fusion proteins with albumin-binding domain for enhanced bioactivity and extended half-life
发表年份:2025 来源杂志:Scientific Reports

113. Hepatic stellate cells shape the ECM-disorganized and immunosuppressive microenvironment via CCL11/CCR3 axis in lenvatinib-treated hepatocellular carcinoma
发表年份:2025 来源杂志:CELLULAR SIGNALLING

114. Blockade of CD47 signaling improves ferroptosis of lung cancer cells via activating Nrf2/FPN signaling
发表年份:2025 来源杂志:CELLULAR SIGNALLING

115. Optical characterization of ocular collagen microstructure and anisotropy in animal and human eyes
发表年份:2025 来源杂志:Biomedical Optics Express

116. Asiaticoside protects against PDF-induced peritoneal fibrosis via suppression of AhR/Nrf2-mediated MMT and oxidative stress
发表年份:2025 来源杂志:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

117. A multi-omics landscape of programmed cell death in acetaminophen-induced acute kidney injury
发表年份:2025 来源杂志:RENAL FAILURE

118. USP18 promote tumor immune evasion in pancreatic cancer through enhancing autolysosome-mediated degradation of MHC-I
发表年份:2025 来源杂志:American Journal of Cancer Research

119. Helicobacter pylori Lipopolysaccharide Upregulates MDM2 via the TLR4/MAPK/AP-1 Pathway to Promote Gastric Cancer Progression
发表年份:2025 来源杂志:DIGESTIVE DISEASES AND SCIENCES

120. Bilirubin Degradation by Hypochlorous Acid: Identification of Products and Their Formation Ex Vivo and In Vivo
发表年份:2025 来源杂志:ChemistrySelect

121. Protocol for co-culture of primary neurons and organotypic hippocampal brain slices from mice
发表年份:2025 来源杂志:STAR Protocols

122. Magnetic mesoporous silica loaded with CGRP antagonist and curcumin coated with cerium oxide for the treatment of neuropathic pain
发表年份:2025 来源杂志:Journal of Materials Science-Materials in Engineering

123. Lighting up arginine metabolism reveals its functional diversity in physiology and pathology
发表年份:2024 来源杂志:Cell Metabolism

124. 2D Differential Metallic Immunopotentiators Drive High Diversity and Capability of Antigen-specific Immunity Against Tumor
发表年份:2024 来源杂志:Advanced Science

125. Propofol Alleviates Anxiety-Like Behaviors Associated with Pain by Inhibiting the Hyperactivity of PVNCRH Neurons via GABAA Receptor β3 Subunits
发表年份:2024 来源杂志:Advanced Science

126. Electromagnetic Cellularized Patch with Wirelessly Electrical Stimulation for Promoting Neuronal Differentiation and Spinal Cord Injury Repair
发表年份:2024 来源杂志:Advanced Science

127. Clec7a Worsens Long-Term Outcomes after Ischemic Stroke by Aggravating Microglia-Mediated Synapse Elimination
发表年份:2024 来源杂志:Advanced Science

128. Oxytocin Protects Nigrostriatal Dopamine Signal via Activating GABAergic Circuit in the MPTP-Induced Parkinson's Disease Model
发表年份:2024 来源杂志:Advanced Science

129. Single-Nucleus RNA Sequencing Reveals That Gabra6+ Neurons in Prefrontal Cortex Promote the Progression of PTSD After Shockwave-Induced TBI
发表年份:2024 来源杂志:Advanced Science

130. Drug evaluation platform based on non-destructive and real-time in situ organoid fate state monitoring by graphene field-effect transistor
发表年份:2024 来源杂志:CHEMICAL ENGINEERING JOURNAL

131. Diselenide bond-stapled β-hairpin peptide-loaded hydrogel system for boosting oncolytic immunotherapy
发表年份:2024 来源杂志:CHEMICAL ENGINEERING JOURNAL

132. A spatiotemporal transcriptomic atlas of mouse placentation
发表年份:2024 来源杂志:Cell Discovery

133. TIPE2 protein restrains invariant NKT activation and protects against immune-mediated hepatitis in mice
发表年份:2024 来源杂志:HEPATOLOGY

134. A natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2
发表年份:2024 来源杂志:Nature Chemical Biology

135. Rational fusion design inspired by cell-penetrating peptide: SS31/S-14G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease
发表年份:2024 来源杂志:Asian Journal of Pharmaceutical Sciences

136. Extending dual-targeting upper-limit in liposomal delivery of lithospermic acid B for Alzheimer's mitochondrial revitalization
发表年份:2024 来源杂志:JOURNAL OF CONTROLLED RELEASE

137. Polyethylene microplastic exposure adversely affects oocyte quality in human and mouse
发表年份:2024 来源杂志:ENVIRONMENT INTERNATIONAL

138. Oncolytic Peptide-Nanoplatform Drives Oncoimmune Response and Reverses Adenosine-Induced Immunosuppressive Tumor Microenvironment
发表年份:2024 来源杂志:Advanced Healthcare Materials

139. PPARα suppresses growth of hepatocellular carcinoma in a high-fat diet context by reducing neutrophil extracellular traps release
发表年份:2024 来源杂志:JHEP Reports

140. Microglia LILRB4 upregulation reduces brain damage after acute ischemic stroke by limiting CD8+ T cell recruitment
发表年份:2024 来源杂志:Journal of Neuroinflammation

141. Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance
发表年份:2024 来源杂志:Journal of Neuroinflammation

142. Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice
发表年份:2024 来源杂志:Journal of Neuroinflammation

143. Ferritin-mediated neutrophil extracellular traps formation and cytokine storm via macrophage scavenger receptor in sepsis-associated lung injury
发表年份:2024 来源杂志:Cell Communication and Signaling

144. Targeting CCL2-CCR2 signaling pathway alleviates macrophage dysfunction in COPD via PI3K-AKT axis
发表年份:2024 来源杂志:Cell Communication and Signaling

145. Absence of Langerhans cells resulted in over-influx of neutrophils and increased bacterial burden in skin wounds
发表年份:2024 来源杂志:Cell Death & Disease

146. Low-dose polystyrene microplastics exposure impairs fertility in male mice with high-fat diet-induced obesity by affecting prostate function
发表年份:2024 来源杂志:ENVIRONMENTAL POLLUTION

147. Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI
发表年份:2024 来源杂志:Cell Reports

148. SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1
发表年份:2024 来源杂志:Cell Reports

149. Dissociation-related behaviors in mice emerge from the inhibition of retrosplenial cortex parvalbumin interneurons
发表年份:2024 来源杂志:Cell Reports

150. Dexmedetomidine facilitates autophagic flux to promote liver regeneration by suppressing GSK3β activity in mouse partial hepatectomy
发表年份:2024 来源杂志:BIOMEDICINE & PHARMACOTHERAPY

151. Bacteroides ovatus alleviates high-fat and high-cholesterol -induced nonalcoholic fatty liver disease via gut-liver axis
发表年份:2024 来源杂志:BIOMEDICINE & PHARMACOTHERAPY

152. Asiatic acid ameliorates doxorubicin-induced cardiotoxicity by promoting FPN-mediated iron export and inhibiting ferroptosis
发表年份:2024 来源杂志:ACTA PHARMACOLOGICA SINICA

153. Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast
发表年份:2024 来源杂志:eLife

154. IGSF9 promotes tumor invasion and metastasis through GSK-3β/β-catenin mediated EMT in lung cancer
发表年份:2024 来源杂志:NEOPLASIA

155. MRG15 promotes cell apoptosis through inhibition of mitophagy in hyperlipidemic acute pancreatitis
发表年份:2024 来源杂志:APOPTOSIS

156. Modulation of cardiac resident macrophages immunometabolism upon high-fat-diet feeding in mice
发表年份:2024 来源杂志:Frontiers in Immunology

157. Depletion of SASP senescent cardiomyocytes with senolytic drugs confers therapeutic effects in doxorubicin-related cardiotoxicity
发表年份:2024 来源杂志:FEBS Journal

158. Quercetin modulates expression of serum exosomal long noncoding RNA NEAT1 to regulate the miR-129-5p/BDNF axis and attenuate cognitive impairment in diabetic mice
发表年份:2024 来源杂志:LIFE SCIENCES

159. Stomach as the target organ of Rickettsia heilongjiangensis infection in C57BL/6 mice identified by click chemistry
发表年份:2024 来源杂志:Communications Biology

160. Bile acid-gut microbiota imbalance in cholestasis and its long-term effect in mice
发表年份:2024 来源杂志:mSystems

161. HMGB2 promotes smooth muscle cell proliferation through PPAR-γ/PGC-1α pathway-mediated glucose changes in aortic dissection
发表年份:2024 来源杂志:ATHEROSCLEROSIS

162. Urolithin A Protects against Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Smooth Muscle Cell Pyroptosis via AMPK/NF-κB/NLRP3 Signaling
发表年份:2024 来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

163. Doxorubicin-Induced Cardiotoxicity Through SIRT1 Loss Potentiates Overproduction of Exosomes in Cardiomyocytes
发表年份:2024 来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

164. Integration and Differentiation of Transplanted Human iPSC-Derived Retinal Ganglion Cell Precursors in Murine Retinas
发表年份:2024 来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

165. Betaine alleviates nonalcoholic fatty liver disease (NAFLD) via a manner involving BHMT/FTO/m6A/ PGC1α signaling
发表年份:2024 来源杂志:JOURNAL OF NUTRITIONAL BIOCHEMISTRY

166. The natural flavonoid pinocembrin shows antithrombotic activity and suppresses septic thrombosis
发表年份:2024 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

167. Gynostemma pentaphyllum Extract Alleviates NASH in Mice: Exploration of Inflammation and Gut Microbiota
发表年份:2024 来源杂志:Nutrients

168. Hypoxia-responsive lncRNA MIR155HG promotes PD-L1 expression in hepatocellular carcinoma cells by enhancing HIF-1α mRNA stability
发表年份:2024 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

169. Anthocyanin-rich lingonberry extract improves intestinal homeostasis based on intestinal stem cells in high-fat-diet-fed mice via gut microbiota-mediated Wnt/PPAR signaling
发表年份:2024 来源杂志:Food Bioscience

170. PNSC5325 prevents acute respiratory distress syndrome by alleviating inflammation and inhibiting extracellular matrix degradation of alveolar macrophages
发表年份:2024 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

171. Therapeutic effects of tripterygium glycosides on periodontitis: Exploring the role of ursolic acid and the RIPK3/NLRP3 signaling pathway
发表年份:2024 来源杂志:INTERNATIONAL IMMUNOPHARMACOLOGY

172. Chuanxiong Renshen Decoction Inhibits Alzheimer’s Disease Neuroinflammation by Regulating PPARγ/NF-κB Pathway
发表年份:2024 来源杂志:Drug Design Development and Therapy

173. Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis
发表年份:2024 来源杂志:Frontiers in Cell and Developmental Biology

174. Phenyllactic acid modulates the gut microbiota, enhances intestinal health, and alleviates physical frailty in aging mice
发表年份:2024 来源杂志:EUROPEAN JOURNAL OF PHARMACOLOGY

175. F-Box and WD repeat domain containing 7 induces infectious osteomyelitis by regulating MYB stability and ubiquitination
发表年份:2024 来源杂志:SCANDINAVIAN JOURNAL OF IMMUNOLOGY

176. Dual engineered bacteria improve inflammatory bowel disease in mice
发表年份:2024 来源杂志:APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

177. Unraveling shared molecular signatures and potential therapeutic targets linking psoriasis and acute myocardial infarction
发表年份:2024 来源杂志:Scientific Reports

178. Anesthetic effects on electrophysiological responses across the visual pathway
发表年份:2024 来源杂志:Scientific Reports

179. Unveiling shared therapeutic targets and pathological pathways between coronary artery disease and major depressive disorder through bioinformatics analysis
发表年份:2024 来源杂志:Scientific Reports

180. Full-length circRNA sequencing method using low-input RNAs and profiling of circRNAs in MPTP-PD mice on a nanopore platform
发表年份:2024 来源杂志:ANALYST

181. Humanin inhibits lymphatic endothelial cells dysfunction to alleviate myocardial infarction-reperfusion injury via BNIP3-mediated mitophagy
发表年份:2024 来源杂志:FREE RADICAL RESEARCH

182. Dapagliflozin ameliorates myocardial infarction injury through AMPKα-dependent regulation of oxidative stress and apoptosis
发表年份:2024 来源杂志:Heliyon

183. SIRT5 safeguards against T-2 toxin induced liver injury by repressing iron accumulation, oxidative stress, and the activation of NLRP3 inflammasome
发表年份:2024 来源杂志:TOXICOLOGY AND APPLIED PHARMACOLOGY

184. Matrix Gla protein suppresses osteoblast senescence and promotes osteogenic differentiation by the PI3K-AKT signaling pathway
发表年份:2024 来源杂志:EXPERIMENTAL CELL RESEARCH

185. METTL3/YTHDF1-mediated m6A modification stabilizes USP12 to deubiquitinate FOXO3 and promote apoptosis in sepsis-induced myocardial dysfunction
发表年份:2024 来源杂志:MOLECULAR IMMUNOLOGY

186. Acquisition and transcriptomic analysis of tissue micro-regions using a capillary-based method
发表年份:2024 来源杂志:JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

187. Docosahexaenoic acid insufficiency impairs placental angiogenesis by repressing the methylene-bridge fatty acylation of AKT in preeclampsia
发表年份:2024 来源杂志:PLACENTA

188. Tanshinone I improves renal fibrosis by promoting gluconeogenesis through upregulation of peroxisome proliferator-activated receptor-γ coactivator 1α
发表年份:2024 来源杂志:RENAL FAILURE

189. Spatial transcriptomic profiling of isolated microregions in tissue sections utilizing laser-induced forward transfer
发表年份:2024 来源杂志:PLoS One

190. Dapagliflozin promotes white adipose tissue browning though regulating angiogenesis in high fat induced obese mice
发表年份:2024 来源杂志:BMC Pharmacology & Toxicology

191. RIP1 inhibition reduces chondrocyte apoptosis through downregulating nuclear factor-kappa B signaling in a mouse osteoarthritis model
发表年份:2024 来源杂志:MOLECULAR BIOLOGY REPORTS

192. Human NMO-IgG Induced Different Pathological and Immunological Changes in the CNS and Peripheral Tissues of Mice
发表年份:2024 来源杂志:Journal of Integrative Neuroscience

193. Repeat administration of human umbilical cord mesenchymal stem cells improves left ventricular diastolic function in mice with heart failure with preserved ejection fraction
发表年份:2024 来源杂志:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

194. Neuron-specific deficiency of autophagy increases neuronal loss in traumatic brain injury
发表年份:2024 来源杂志:PNAS Nexus

195. Establishment of a Mouse Model for Porokeratosis Due to Mevalonate Diphosphate Decarboxylase Deficiency
发表年份:2024 来源杂志:SKIN RESEARCH AND TECHNOLOGY

196. Dexmedetomidine ameliorates x-ray-induced myocardial injury via alleviating cardiomyocyte apoptosis and autophagy
发表年份:2024 来源杂志:BMC Cardiovascular Disorders

197. Protocol for building an in vitro model of M2-like tumor-associated macrophages with lactic acid or conditioned medium from Lewis cells
发表年份:2024 来源杂志:STAR Protocols

198. Urea cycle activation triggered by host-microbiota maladaptation driving colorectal tumorigenesis
发表年份:2023 来源杂志:Cell Metabolism

199. Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
发表年份:2023 来源杂志:Cell Stem Cell

200. Self-maintaining macrophages within the kidney contribute to salt and water balance by modulating kidney sympathetic nerve activity
发表年份:2023 来源杂志:KIDNEY INTERNATIONAL

201. Representation and control of pain and itch by distinct prefrontal neural ensembles
发表年份:2023 来源杂志:NEURON

202. Semaphorin3A Exacerbates Cardiac Microvascular Rarefaction in Pressure Overload-Induced Heart Disease
发表年份:2023 来源杂志:Advanced Science

203. Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages
发表年份:2023 来源杂志:Theranostics

204. Cisplatin attenuates taste cell homeostasis and induces inflammatory activation in the circumvallate papilla
发表年份:2023 来源杂志:Theranostics

205. Mass Spectrometry Imaging-Based Single-Cell Lipidomics Profiles Metabolic Signatures of Heart Failure
发表年份:2023 来源杂志:Research

206. Atypical antipsychotics antagonize GABAA receptors in the ventral tegmental area GABA neurons to relieve psychotic behaviors
发表年份:2023 来源杂志:MOLECULAR PSYCHIATRY

207. Multilineage contribution of CD34+ cells in cardiac remodeling after ischemia/reperfusion injury
发表年份:2023 来源杂志:BASIC RESEARCH IN CARDIOLOGY

208. The critical role of KLF4 in regulating the activation of A1/A2 reactive astrocytes following ischemic stroke
发表年份:2023 来源杂志:Journal of Neuroinflammation

209. HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway
发表年份:2023 来源杂志:Cell Reports

210. IFN-γ blockade after genetic inhibition of PD-1 aggravates skeletal muscle damage and impairs skeletal muscle regeneration
发表年份:2023 来源杂志:CELLULAR & MOLECULAR BIOLOGY LETTERS

211. Oral Nanoparticles of SNX10-shRNA Plasmids Ameliorate Mouse Colitis
发表年份:2023 来源杂志:International Journal of Nanomedicine

212. Dopamine D1 receptor agonist alleviates acute lung injury via modulating inflammatory responses in macrophages and barrier function in airway epithelial cells
发表年份:2023 来源杂志:FREE RADICAL BIOLOGY AND MEDICINE

213. Human Proteome Microarray identifies autoantibodies to tumor-associated antigens as serological biomarkers for the diagnosis of hepatocellular carcinoma
发表年份:2023 来源杂志:Molecular Oncology

214. Downregulated VISTA enhances Th17 differentiation and aggravates inflammation in patients with acute-on-chronic liver failure
发表年份:2023 来源杂志:Hepatology International

215. Decoding Single-cell Landscape and Intercellular Crosstalk in the Transplanted Liver
发表年份:2023 来源杂志:TRANSPLANTATION

216. A novel His-tag-binding aptamer for recombinant protein detection and T cell-based immunotherapy
发表年份:2023 来源杂志:TALANTA

217. Dihydromyricetin Protects Intestinal Barrier Integrity by Promoting IL-22 Expression in ILC3s through the AMPK/SIRT3/STAT3 Signaling Pathway
发表年份:2023 来源杂志:Nutrients

218. RAGE inhibition alleviates lipopolysaccharides-induced lung injury via directly suppressing autophagic apoptosis of type II alveolar epithelial cells
发表年份:2023 来源杂志:RESPIRATORY RESEARCH

219. Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Geraniol alleviates acute liver failure
发表年份:2023 来源杂志:BIOCHEMICAL PHARMACOLOGY

220. Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice
发表年份:2023 来源杂志:iScience

221. Exploring the potential targets of Biling Weitong Granules on visceral hypersensitivity through integration of network pharmacology and in vivo analysis
发表年份:2023 来源杂志:JOURNAL OF ETHNOPHARMACOLOGY

222. Polydatin Alleviates Chronic Stress-Induced Depressive and Anxiety-like Behaviors in a Mouse Model
发表年份:2023 来源杂志:ACS Chemical Neuroscience

223. Sodium butyrate ameliorates gut dysfunction and motor deficits in a mouse model of Parkinson’s disease by regulating gut microbiota
发表年份:2023 来源杂志:Frontiers in Aging Neuroscience

224. Selective PPARγ modulator diosmin improves insulin sensitivity and promotes browning of white fat
发表年份:2023 来源杂志:JOURNAL OF BIOLOGICAL CHEMISTRY

225. Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3–NFS1 axis in doxorubicin-induced cardiotoxicity
发表年份:2023 来源杂志:CELLULAR SIGNALLING

226. Serotonin/5-HT7 receptor provides an adaptive signal to enhance pigmentation response to environmental stressors through cAMP-PKA-MAPK, Rab27a/RhoA, and PI3K/AKT signaling pathways
发表年份:2023 来源杂志:FASEB JOURNAL

227. Exosomes derived miR-362 exacerbates pneumonia by increasing Interleukin-6 via targeting VENTX
发表年份:2023 来源杂志:ENVIRONMENTAL TOXICOLOGY

228. C1q Confers Protection Against Cryptococcal Lung Infection by Alleviating Inflammation and Reducing Cryptococcal Virulence
发表年份:2023 来源杂志:Open Forum Infectious Diseases

229. Liraglutide alleviates myocardial ischemia‒reperfusion injury in diabetic mice
发表年份:2023 来源杂志:MOLECULAR AND CELLULAR ENDOCRINOLOGY

230. Targeting Labile Iron-Mediated Ferroptosis Provides a Potential Therapeutic Strategy for Rhabdomyolysis-Induced Acute Kidney Injury
发表年份:2023 来源杂志:ACS Chemical Biology

231. Sweroside alleviates hepatic steatosis in part by activating AMPK/mTOR-mediated autophagy in mice
发表年份:2023 来源杂志:JOURNAL OF CELLULAR BIOCHEMISTRY

232. Role of SIRT5 in the analgesic effectiveness of moxibustion at ST36 in mice with inflammatory pain
发表年份:2023 来源杂志:Heliyon

233. Vascular endothelial-derived Von Willebrand factor inhibits lung cancer progression through the αvβ3/ERK1/2 axis
发表年份:2023 来源杂志:TOXICOLOGY AND APPLIED PHARMACOLOGY

234. The Tet2–Upf1 complex modulates mRNA stability under stress conditions
发表年份:2023 来源杂志:Frontiers in Genetics

235. Angiotensin II type 2 receptor agonist attenuates LPS-induced acute lung injury through modulating THP-1-derived macrophage reprogramming
发表年份:2023 来源杂志:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

236. Interleukin-33 Potentiates TGF-β Signaling to Regulate Intestinal Stem Cell Regeneration After Radiation Injury
发表年份:2023 来源杂志:CELL TRANSPLANTATION

237. Macrophages promote heat stress nephropathy in mice via the C3a-C3aR-TNF pathway
发表年份:2023 来源杂志:IMMUNOBIOLOGY

238. BMP9 ameliorates amyloid pathology by promoting low-density lipoprotein receptor-related protein 1 expression in APP/PS1 transgenic mice
发表年份:2023 来源杂志:NEUROSCIENCE LETTERS

239. Protocol for engineering E. coli Nissle 1917 to diagnose, record, and ameliorate inflammatory bowel disease in mice
发表年份:2023 来源杂志:STAR Protocols

240. Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice
发表年份:2022 来源杂志:Cell Host & Microbe

241. Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents
发表年份:2022 来源杂志:Theranostics

242. Identification of Periosteal Osteogenic Progenitors in Jawbone
发表年份:2022 来源杂志:JOURNAL OF DENTAL RESEARCH

243. Analysis of Mononuclear Phagocytes Disclosed the Establishment Processes of Two Macrophage Subsets in the Adult Murine Kidney
发表年份:2022 来源杂志:Frontiers in Immunology

244. Prussian Blue Scavenger Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Inflammation and Reducing Oxidative Stress
发表年份:2022 来源杂志:Frontiers in Immunology

245. A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer
发表年份:2022 来源杂志:eLife

246. The Role of CD147 in Pathological Cardiac Hypertrophy Is Regulated by Glycosylation
发表年份:2022 来源杂志:Oxidative Medicine and Cellular Longevity

247. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice
发表年份:2022 来源杂志:ACTA PHARMACOLOGICA SINICA

248. Advanced paternal age increased metabolic risks in mice offspring
发表年份:2022 来源杂志:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

249. Gynostemma pentaphyllum polysaccharides ameliorate non-alcoholic steatohepatitis in mice associated with gut microbiota and the TLR2/NLRP3 pathway
发表年份:2022 来源杂志:Frontiers in Endocrinology

250. Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity
发表年份:2022 来源杂志:Frontiers in Endocrinology

251. Cell-Penetrating Botulinum Neurotoxin Type A With Improved Cellular Uptake and Therapeutic Index
发表年份:2022 来源杂志:Frontiers in Bioengineering and Biotechnology

252. Comprehensive Transcriptome Profiling of NAFLD- and NASH-Induced Skeletal Muscle Dysfunction
发表年份:2022 来源杂志:Frontiers in Endocrinology

253. Bie-Jia-Ruan-Mai-Tang, a Chinese Medicine Formula, Inhibits Retinal Neovascularization in Diabetic Mice Through Inducing the Apoptosis of Retinal Vascular Endothelial Cells.
发表年份:2022 来源杂志:Frontiers in Cardiovascular Medicine

254. Ileal FXR-FGF15/19 signaling activation improves skeletal muscle loss in aged mice
发表年份:2022 来源杂志:MECHANISMS OF AGEING AND DEVELOPMENT

255. Complete Shift in Glycosyl Donor Specificity in Mammalian, but not C. elegans β1,4-GalT1 Y286L mutants, Enables the Synthesis of N,N-Diacetyllactosamine
发表年份:2022 来源杂志:ChemCatChem

256. A self-ratiometric and selective electrochemical sensor for the detection of tyrosinase in mouse brain homogenate
发表年份:2022 来源杂志:ANALYST

257. Protein arginine methyltransferase 3 inhibits renal tubulointerstitial fibrosis through asymmetric dimethylarginine
发表年份:2022 来源杂志:Frontiers in Medicine

258. Identification of novel key genes and potential candidate small molecule drugs in diabetic kidney disease using comprehensive bioinformatics analysis
发表年份:2022 来源杂志:Frontiers in Genetics

259. PCSK9 mediates dyslipidemia induced by olanzapine treatment in schizophrenia patients
发表年份:2022 来源杂志:PSYCHOPHARMACOLOGY

260. Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing JAK1/STAT1 pathway
发表年份:2022 来源杂志:Biochemistry and Cell Biology

261. Identification of circular RNA biomarkers for Pien Tze Huang treatment of CCl4‑induced liver fibrosis using RNA‑sequencing
发表年份:2022 来源杂志:Molecular Medicine Reports

262. Sodium Tanshinone IIA Sulfonate Improves Adverse Ventricular Remodeling Post-MI by Reducing Myocardial Necrosis, Modulating Inflammation, and Promoting Angiogenesis
发表年份:2022 来源杂志:CURRENT PHARMACEUTICAL DESIGN

263. NLRP3 Inhibitor Tranilast Attenuates Gestational Diabetes Mellitus in a Genetic Mouse Model
发表年份:2022 来源杂志:DRUGS IN R&D

264. Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease
发表年份:2021 来源杂志:Bioactive Materials

265. M351-0056 is a novel low MW compound modulating the actions of the immune-checkpoint protein VISTA
发表年份:2021 来源杂志:BRITISH JOURNAL OF PHARMACOLOGY

266. Ablation of Survivin in T Cells Attenuates Acute Allograft Rejection after Murine Heterotopic Heart Transplantation by Inducing Apoptosis
发表年份:2021 来源杂志:Frontiers in Immunology

267. Highly Stable Electrochemical Probe with Bidentate Thiols for Ratiometric Monitoring of Endogenous Polysulfide in Living Mouse Brains
发表年份:2021 来源杂志:ANALYTICAL CHEMISTRY

268. Methyl Diet Enhanced Sepsis-Induced Mortality Through Altering Gut Microbiota
发表年份:2021 来源杂志:Journal of Inflammation Research

269. Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling
发表年份:2021 来源杂志:ANNALS OF MEDICINE

270. Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy
发表年份:2021 来源杂志:Frontiers in Genetics

271. Effect of κ-carrageenan on glucolipid metabolism and gut microbiota in high-fat diet-fed mice
发表年份:2021 来源杂志:Journal of Functional Foods

272. The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells
发表年份:2021 来源杂志:Scientific Reports

273. Low bias multiple displacement amplification with confinement effect based on agarose gel
发表年份:2021 来源杂志:ANALYTICAL AND BIOANALYTICAL CHEMISTRY

274. Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy
发表年份:2021 来源杂志:American Journal of Translational Research

275. Activation of Gonadotropin-releasing Hormone Receptor Impedes the Immunosuppressive Activity of Decidual Regulatory T Cells via Deactivating the Mechanistic Target of Rapamycin Signaling
发表年份:2021 来源杂志:IMMUNOLOGICAL INVESTIGATIONS

276. Brain-derived neurotrophic factor attenuates cognitive impairment and motor deficits in a mouse model of Parkinson's disease
发表年份:2021 来源杂志:Brain and Behavior

277. miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury
发表年份:2021 来源杂志:EXPERIMENTAL BIOLOGY AND MEDICINE

278. Autophagy-lysosome inhibitor chloroquine prevents CTLA-4 degradation of T cells and attenuates acute rejection in murine skin and heart transplantation
发表年份:2020 来源杂志:Theranostics

279. Dexmedetomidine Activation of Dopamine Neurons in the Ventral Tegmental Area Attenuates the Depth of Sedation in Mice
发表年份:2020 来源杂志:ANESTHESIOLOGY

280. The triterpenoid sapogenin (2α-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling
发表年份:2020 来源杂志:Cell Death & Disease

281. An electrochemical sensor for bacterial lipopolysaccharide detection based on dual functional Cu2+-modified metal–organic framework nanoparticles
发表年份:2020 来源杂志:MICROCHIMICA ACTA

282. Salmonella and S. aureus Escape From the Clearance of Macrophages via Controlling TFEB
发表年份:2020 来源杂志:Frontiers in Microbiology

283. MiR-1-3p regulates the differentiation of mesenchymal stem cells to prevent osteoporosis by targeting secreted frizzled-related protein 1
发表年份:2020 来源杂志:BONE

284. A Brain Signaling Framework for Stress-Induced Depression and Ketamine Treatment Elucidated by Phosphoproteomics
发表年份:2020 来源杂志:Frontiers in Cellular Neuroscience

285. Fisetin regulates gut microbiota to decrease CCR9+/CXCR3+/CD4+ T-lymphocyte count and IL-12 secretion to alleviate premature ovarian failure in mice
发表年份:2020 来源杂志:American Journal of Translational Research

286. Extracellular ubiquitin promotes hepatoma metastasis by mediating M2 macrophage polarization via the activation of the CXCR4/ERK signaling pathway
发表年份:2020 来源杂志:Annals of Translational Medicine

287. Emodin ameliorates tubulointerstitial fibrosis in obstructed kidneys by inhibiting EZH2
发表年份:2020 来源杂志:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

288. miR-34a attenuates myocardial fibrosis in diabetic cardiomyopathy mice via targeting Pin-1
发表年份:2020 来源杂志:CELL BIOLOGY INTERNATIONAL

289. Linc-FOXD3 knockdown enhances hippocampal NSCs activation through upregulation of the Wnt/β-catenin pathway
发表年份:2020 来源杂志:NEUROSCIENCE LETTERS

290. The effect of Tauroursodeoxycholic acid (TUDCA) and gut microbiota on murine gallbladder stone formation
发表年份:2020 来源杂志:Annals of Hepatology

291. Exercise Preconditioning Protects against Acute Cardiac Injury Induced by Lipopolysaccharide Through General Control Nonderepressible 2 Kinase
发表年份:2020 来源杂志:International Heart Journal

292. MRG15 orchestrates rhythmic epigenomic remodelling and controls hepatic lipid metabolism
发表年份:2020 来源杂志:Nature Metabolism

293. Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening
发表年份:2019 来源杂志:Autophagy

294. Pravastatin regulates host foreign-body reaction to polyetheretherketone implants via miR-29ab1-mediated SLIT3 upregulation
发表年份:2019 来源杂志:BIOMATERIALS

295. Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation
发表年份:2019 来源杂志:Alzheimers Research & Therapy

296. miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity
发表年份:2019 来源杂志:Cell Death & Disease

297. Longevity Effect of Liuwei Dihuang in Both Caenorhabditis Elegans and Aged Mice
发表年份:2019 来源杂志:Aging and Disease

298. P11 Loss-of-Function is Associated with Decreased Cell Proliferation and Neurobehavioral Disorders in Mice
发表年份:2019 来源杂志:International Journal of Biological Sciences

299. Stimulation of histamine H4 receptor participates in cold-induced browning of subcutaneous white adipose tissue
发表年份:2019 来源杂志:AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

300. Herbs-partitioned moxibustion improves intestinal epithelial tight junctions by upregulating A20 expression in a mouse model of Crohn’s disease
发表年份:2019 来源杂志:BIOMEDICINE & PHARMACOTHERAPY

301. Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation-induced oral mucositis in mice
发表年份:2019 来源杂志:American Journal of Translational Research

302. OPG is Required for the Postnatal Maintenance of Condylar Cartilage
发表年份:2019 来源杂志:CALCIFIED TISSUE INTERNATIONAL

303. Decreased cpg15 augments oxidative stress in sleep deprived mouse brain
发表年份:2019 来源杂志:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

304. Alcohol and HBV synergistically promote hepatic steatosis
发表年份:2019 来源杂志:Annals of Hepatology

305. Effects of farnesoid-X-receptor SUMOylation mutation on myocardial ischemia/reperfusion injury in mice
发表年份:2018 来源杂志:EXPERIMENTAL CELL RESEARCH

306. Nerve growth factor metabolic dysfunction contributes to sevoflurane-induced cholinergic degeneration and cognitive impairments
发表年份:2018 来源杂志:BRAIN RESEARCH

307. Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
发表年份:2018 来源杂志:Molecular Medicine Reports

308. Berberine attenuate staphylococcal enterotoxin B-mediated acute liver injury via regulating HDAC expression
发表年份:2018 来源杂志:AMB Express

309. Contradictory effects of mitochondria- and non-mitochondria-targeted antioxidants on hepatocarcinogenesis by altering DNA repair in mice
发表年份:2017 来源杂志:HEPATOLOGY

310. RNAi targeting Nogo Receptor enhanced survival and proliferation of murine retinal ganglion cells during N-methyl-D-aspartate-induced optic nerve crush
发表年份:2017 来源杂志:Oncotarget

311. Depletion of circulating monocytes suppresses IL-17 and HMGB1 expression in mice with LPS-induced acute lung injury
发表年份:2017 来源杂志:AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

312. SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction
发表年份:2017 来源杂志:MOLECULAR AND CELLULAR ENDOCRINOLOGY

313. Knockout of BRD7 results in impaired spermatogenesis and male infertility.
发表年份:2016 来源杂志:Scientific Reports

314. NMNAT3 is involved in the protective effect of SIRT3 in Ang II-induced cardiac hypertrophy
发表年份:2016 来源杂志:EXPERIMENTAL CELL RESEARCH

315. TDRP deficiency contributes to low sperm motility and is a potential risk factor for male infertility
发表年份:2016 来源杂志:American Journal of Translational Research

316. Medium-chain triglycerides promote macrophage reverse cholesterol transport and improve atherosclerosis in ApoE-deficient mice fed a high-fat diet
发表年份:2016 来源杂志:NUTRITION RESEARCH

317. Hepatitis B surface antigen (HBsAg) and core antigen (HBcAg) combine CpG oligodeoxynucletides as a novel therapeutic vaccine for chronic hepatitis B infection
发表年份:2015 来源杂志:VACCINE

318. Effects of Dendritic Cells from Hepatitis B Virus Transgenic Mice-Stimulated Autologous Lymphocytes on Hepatitis B Virus Replication: A Study on the Impact of Specific Sensitized Effector Cells on In Vitro Virus Replication
发表年份:2015 来源杂志:VIRAL IMMUNOLOGY

319. Cytotoxic T lymphocyte antigen 4 decreases humoral and cellular immunity by adenovirus to enhance target GFP gene transfer in C57BL/6 mice
发表年份:2015 来源杂志:IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

320. Establishment of a transgenic mouse model of corneal dystrophy overexpressing human BIGH3
发表年份:2013 来源杂志:INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

321. An essential role for DNA methyltransferase 3a in melanoma tumorigenesis
发表年份:2009 来源杂志:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

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