Il16-Luc-2A-EGFP

品系全名

C57BL/6JSmo-Il16em1(Luc-eGFP)Smoc

目录号

NM-KI-00028

品系状态

胚胎冻存

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基因信息

基因名
Il16

品系描述

将luciferase-2a-egfp-pA表达片段插入到Il16翻译起始位点ATG后。该品系小鼠Il16基因表达缺失,同时该内源启动子驱动报告基因表达。报告基因的表达强度反映了Il16的激活程度,可以在活体中实时跟踪炎症因子Il16,将表达模式可视化。这些小鼠模型对于免疫细胞分类与示踪、免疫过程与疾病机制研究、药物靶点研究与药物开发等领域都具有非常重要的意义与价值。
应用领域:炎症与免疫;示踪

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