M-NSG

1. Functional Precision Oncology Platform of BRAFV600E-Mutated Colorectal Cancer Organoids Predicts Therapy Response and Reveals RNF43-Mediated Immunogenicity
发表年份：2026 来源杂志：DRUG RESISTANCE UPDATES

2. Shear stress governs hematopoietic stem cell fate to promote inflammation-induced aging
发表年份：2026 来源杂志：Nature Aging

3. FOSL1 Orchestrates Epigenetic Reprogramming of Anaplastic Thyroid Cancer and Suppresses Natural Killer Cell-Mediated Antitumor Immunity
发表年份：2026 来源杂志：CANCER RESEARCH

4. Structure–Activity-Driven Multicompartment Lipid Nanoparticles for Synergistic mRNA and siRNA Codelivery in Acute Myeloid Leukemia
发表年份：2026 来源杂志：Journal of the American Chemical Society

5. A RANKL+/CXCR4+ B cell population accumulates in bone marrow and causes age-related osteoporosis in mice
发表年份：2026 来源杂志：Bone Research

6. Apoptotic bodies derived from human umbilical cord mesenchymal stem cells improve recovery from myocardial infarction in swine
发表年份：2026 来源杂志：Autophagy

7. ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC-I Antigen Presentation That Promotes Tumor Immune Evasion
发表年份：2026 来源杂志：Advanced Science

8. PD-L1-Binding Antigen Presenters: Redirecting Vaccine-Induced Antibodies for Cancer Immunotherapy
发表年份：2026 来源杂志：Advanced Science

9. Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury
发表年份：2026 来源杂志：Advanced Science

10. Vessels encapsulating tumor clusters promote non-invasive metastasis of hepatocellular carcinoma by shaping an immunosuppressive microenvironment
发表年份：2026 来源杂志：JOURNAL OF CLINICAL INVESTIGATION

11. Genome-wide screenings identify BAP1 as a synthetic-lethality target with CDK4/6 inhibitors
发表年份：2026 来源杂志：Science Advances

12. Interleukin-27 remodels the bone marrow niche to suppress B-cell development and leukaemia progression in mouse models
发表年份：2026 来源杂志：EBioMedicine

13. Indole-3-Carbaldehyde from Limosilactobacillus reuteri Boosts Chemotherapy Response in Diffuse Large B Cell Lymphoma by Blocking the Mechanistic Target of Rapamycin Pathway
发表年份：2026 来源杂志：Research

14. mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy
发表年份：2026 来源杂志：Cell Reports Medicine

15. Targeting endosomal trafficking-mediated antigen escape to resensitize myeloma to CAR-T therapy
发表年份：2026 来源杂志：Journal for ImmunoTherapy of Cancer

16. A bispecific nanobody-drug conjugate targeting TROP2 and c-Met for low-concentration, single-dose treatment of pancreatic cancer
发表年份：2026 来源杂志：Cell Reports Medicine

17. SMAD7 drives natural killer cell antitumor activity through canonical TGF-β blockade and non-canonical transcriptional activation of STAT5A
发表年份：2026 来源杂志：Journal for ImmunoTherapy of Cancer

18. Non-competing Trop2 nanobody-based radiotheranostics for precision imaging and therapy of pancreatic cancer
发表年份：2026 来源杂志：Materials Today Bio

19. Targeting FGFR1-regulated SPP1 signaling repolarizes immunosuppressive macrophages and sensitizes Hepatocellular Carcinoma to anti-PD-1 therapy
发表年份：2026 来源杂志：CANCER LETTERS

20. USP22 Inhibition Potentiates GPC3 Chimeric Antigen Receptor Macrophages Efficacy in Hepatocellular Carcinoma by Downregulating Tumor CD24 Expression
发表年份：2026 来源杂志：CANCER LETTERS

21. USP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 Deubiquitination
发表年份：2026 来源杂志：International Journal of Biological Sciences

22. Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy
发表年份：2026 来源杂志：DEVELOPMENTAL CELL

23. A shark VNAR-IL-15 fusion protein that suppresses TROP2+ tumor growth
发表年份：2026 来源杂志：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

24. Silencing SFRP1 in bone mesenchymal stem cells alleviates pediatric B-ALL-driven bone loss by activating Wnt/β-catenin signaling
发表年份：2026 来源杂志：Journal of Orthopaedic Translation

25. Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC class I-deficient solid tumors
发表年份：2026 来源杂志：Cell Reports

26. Discovery of Oxime Ether Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer
发表年份：2026 来源杂志：JOURNAL OF MEDICINAL CHEMISTRY

27. Halofuginone exerts broad-spectrum cytotoxic effects by regulating p-eIF2α-S100A8/A9-calcium signaling, inhibiting global protein synthesis, and reversing the resistance of idarubicin in acute myeloid leukemia
发表年份：2026 来源杂志：Chinese Medicine

28. Lycorine suppresses cell growth and attenuates stemness through PI3K/AKT pathway in ovarian cancer
发表年份：2026 来源杂志：BIOCHEMICAL PHARMACOLOGY

29. Multi-omics classification of acute myeloid leukemia guides drug combinations to overcome Venetoclax resistance
发表年份：2026 来源杂志：Cancer Drug Resistance

30. ERCC6L promotes cutaneous melanoma progression via PLK1-mediated aerobic glycolysis: Mechanisms and therapeutic implications
发表年份：2026 来源杂志：LIFE SCIENCES

31. A novel human acute myeloid leukemia cell line SDEY-AML1 with KMT2A: MLLT3, IKZF1: EVX1 fusions exhibits high tumorigenicity in NSG mice
发表年份：2026 来源杂志：Scientific Reports

32. RARG promotes gastric cancer progression by activating PMEPA1 transcription and Wnt/β-catenin signalling
发表年份：2026 来源杂志：CELLULAR SIGNALLING

33. Tumor-Derived Exosomal PDLIM1 Promotes Angiogenesis and Tumor Progression in Papillary Thyroid Carcinoma: Insights From Integrated Single-Cell Transcriptomics and Exosomal Proteomics
发表年份：2026 来源杂志：Cancer Management and Research

34. Preclinical Evaluation of AHT-102, a CLDN18.2 × CD3 Bispecific Antibody: Pharmacokinetics, Anti-Tumor Efficacy, Tissue Distribution, and Safety Profile
发表年份：2026 来源杂志：DRUGS IN R&D

35. Construction of a novel B7H3 VHH-Fc antibody with potent antitumor activity and NK/T cell activation
发表年份：2026 来源杂志：PROTEIN EXPRESSION AND PURIFICATION

36. Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
发表年份：2025 来源杂志：NATURE

37. SARDH in the 1-C metabolism sculpts the T-cell fate and serves as a potential cancer therapeutic target
发表年份：2025 来源杂志：Cellular & Molecular Immunology

38. TRAF3IP2-AS1 Deficiency Induces Necroptosis to Promote Pancreatic Cancer Liver Metastasis
发表年份：2025 来源杂志：CANCER RESEARCH

39. MEN1 Promotes Ferroptosis by Disrupting CD44 Alternative Splicing to Suppress Lung Cancer
发表年份：2025 来源杂志：CANCER RESEARCH

40. Cholangiocarcinoma PDHA1 succinylation suppresses macrophage antigen presentation via alpha-ketoglutaric acid accumulation
发表年份：2025 来源杂志：Nature Communications

41. USP20 as a super-enhancer-regulated gene drives T-ALL progression via HIF1A deubiquitination
发表年份：2025 来源杂志：Acta Pharmaceutica Sinica B

42. OX40–heparan sulfate binding facilitates CAR T cell penetration into solid tumors in mice
发表年份：2025 来源杂志：Science Translational Medicine

43. Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH-Mutant Glioma
发表年份：2025 来源杂志：Advanced Science

44. Chemotherapy-Mediated Induction of PD-L1 via SEI1 Facilitates Myeloma Immune Evasion
发表年份：2025 来源杂志：Advanced Science

45. DDAH1 Promotes Cisplatin Chemoresistance in Patients with Locally Advanced Nasopharyngeal Carcinoma via the EGFR-JAK2-STAT3 Pathway
发表年份：2025 来源杂志：Advanced Science

46. SenExo-cCCT2 Reprograms Senescence Response and Anti-Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma
发表年份：2025 来源杂志：Advanced Science

47. An Engineered Probiotic Consortium Based on Quorum-Sensing for Colorectal Cancer Immunotherapy
发表年份：2025 来源杂志：Advanced Science

48. SIRT5 inhibition impairs mitochondrial metabolism and enhances venetoclax-induced elimination of acute myeloid leukemia cells
发表年份：2025 来源杂志：LEUKEMIA

49. Liquid-liquid phase separation of ZHX2 protects DLBCL cells against ferroptosis through induction of SLC3A2
发表年份：2025 来源杂志：LEUKEMIA

50. STING mediates increased self-renewal and lineage skewing in DNMT3A-mutated hematopoietic stem/progenitor cells
发表年份：2025 来源杂志：LEUKEMIA

51. 5-FU@HFn combined with decitabine induces pyroptosis and enhances antitumor immunotherapy for chronic myeloid leukemia
发表年份：2025 来源杂志：JOURNAL OF NANOBIOTECHNOLOGY

52. Asparaginase Enhances CAR-T Cell Antitumor Immunity by Asparagine Metabolic Reprogramming and Induction of Central Memory Phenotype in ALL
发表年份：2025 来源杂志：MOLECULAR THERAPY

53. BCL-2 mutant B7H6-CAR-T cells synergized with venetoclax for treating small cell lung cancer
发表年份：2025 来源杂志：Journal for ImmunoTherapy of Cancer

54. JMJD3 upregulates ALOX5 to drive malignancy and concomitant ferroptosis sensitivity in gastric cancer
发表年份：2025 来源杂志：Cell Death & Disease

55. Low SVEP1 in intrahepatic cholangiocarcinoma mediates phenotype switching-driven metastasis by Jag2/Notch1/Hes5
发表年份：2025 来源杂志：Cell Death & Disease

56. UHRF1-mediated epigenetic reprogramming regulates glycolysis to promote progression of B-cell acute lymphoblastic leukemia
发表年份：2025 来源杂志：Cell Death & Disease

57. ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation
发表年份：2025 来源杂志：Cell Death & Disease

58. Targeting FAM111B attenuates mitophagy and increases the sensitivity to lenvatinib treatment by increasing MFN2 stability in hepatocellular carcinoma
发表年份：2025 来源杂志：Cell Death & Disease

59. Tryptamine-Functionalized Lipid Nanocarriers Co-delivering SMO/BRD4 Inhibitors for Synergistic Medulloblastoma Therapy
发表年份：2025 来源杂志：Biomaterials Research

60. Ephrin A1 functions as a ligand of EGFR to promote EMT and metastasis in gastric cancer
发表年份：2025 来源杂志：EMBO JOURNAL

61. Combination therapy with Chicoric acid and PD-1/PD-L1 blockade improves the immunotherapy response in patient-derived ovarian cancer xenograft model
发表年份：2025 来源杂志：Cell Communication and Signaling

62. Retinoic acid enhances γδ T cell cytotoxicity in nasopharyngeal carcinoma by reversing immune exhaustion
发表年份：2025 来源杂志：Cell Communication and Signaling

63. Histone acetylation activated-IGF2BP3 regulates cyclin D1 mRNA stability to drive cell cycle transition and tumor progression of hepatocellular carcinoma
发表年份：2025 来源杂志：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

64. Deoxypodophyllotoxin inhibited the growth of malignant pleural mesothelioma by inducing necroptosis and mitotic catastrophe
发表年份：2025 来源杂志：PHYTOMEDICINE

65. CBX5 loss drives Pl3Kδ inhibitor resistance in mantle cell lymphoma and propolis restores sensitivity by inducing CBX5-mediated ferroptosis
发表年份：2025 来源杂志：PHYTOMEDICINE

66. Single-cell transcriptome analysis identifies MIF as a novel tumor-associated neutrophil marker for pancreatic ductal adenocarcinoma
发表年份：2025 来源杂志：npj Precision Oncology

67. Activation of PERK/eIF2α/ATF4 signaling inhibits ERα expression in breast cancer
发表年份：2025 来源杂志：NEOPLASIA

68. T cell receptor-like antibody specifically targets and eliminates cells infected with cytomegalovirus
发表年份：2025 来源杂志：Journal of Translational Medicine

69. Microenvironmental β-TrCP negates amino acid transport to trigger CD8+ T cell exhaustion in human non-small cell lung cancer
发表年份：2025 来源杂志：Cell Reports

70. LAMP5 modulates IRF4 stability and nuclear transport: a critical mechanism in myeloma progression and therapy
发表年份：2025 来源杂志：ONCOGENE

71. KRT5high TP63-expressing urothelial basal cells act as a driver to bladder urothelium regeneration in rabbit
发表年份：2025 来源杂志：Stem Cell Research & Therapy

72. Metrnl protects intestinal barrier function by regulating tight junctions via the IKKβ/IκBα/NFκB/MLCK/MLC signaling pathway
发表年份：2025 来源杂志：Cell Death Discovery

73. High-glucose-associated YTHDC1 lactylation reduces the sensitivity of bladder cancer to enfortumab vedotin therapy
发表年份：2025 来源杂志：Cell Reports

74. ENPP1 governs the metabolic regulation of effector T cells in autoimmunity by detecting cytosolic mitochondrial DNA
发表年份：2025 来源杂志：Cell Reports

75. Discovery of P11–2: A Potent First-in-Class MNK1-Targeting PROTAC Degrader for the Treatment of Cancer
发表年份：2025 来源杂志：JOURNAL OF MEDICINAL CHEMISTRY

76. Deciphering the role of IGF2BP2 and PRMT5 in gallbladder cancer progression: insights from multi-omics analysis
发表年份：2025 来源杂志：BRITISH JOURNAL OF CANCER

77. The pronounced cytotoxic effects of chimeric antigen receptor T cells targeting B7-H3 in organoids and liver xenografts derived from colorectal cancer patients
发表年份：2025 来源杂志：BRITISH JOURNAL OF CANCER

78. Tumor-derived CD84 promotes growth of acute myeloid leukemia cells via regulating non-homologous DNA end joining pathway
发表年份：2025 来源杂志：MOLECULES AND CELLS

79. Coke Oven Emission Exposure Triggers Malignant Transformation of Lung Epithelial Cells by SFTA1P-Dependent Alteration of Acetyl-CoA Metabolism
发表年份：2025 来源杂志：Environment & Health

80. Targeted editing of CCL5 with CRISPR-Cas9 nanoparticles enhances breast cancer immunotherapy
发表年份：2025 来源杂志：APOPTOSIS

81. COL4A2 drives ECM remodeling and stiffness increasing to promote breast cancer metastasis via YAP signaling pathway in dECM induced models
发表年份：2025 来源杂志：Biomaterials Advances

82. Marine natural product Methyl mycophenolate inhibits gastric cancer growth through regulating p53 and the downstream pathways
发表年份：2025 来源杂志：Cancer Cell International

83. Chemical induction of ferroptosis through GPX4 inhibition: Rational Design of Triazole-Benzoxazine Hybrids for melanoma therapy
发表年份：2025 来源杂志：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

84. Combination of anlotinib with immunotherapy enhanced both anti-angiogenesis and immune response in high-grade serous ovarian cancer
发表年份：2025 来源杂志：Frontiers in Immunology

85. High expression of CXCL13 predicts a favorable response to immunotherapy by upregulating CXCR5+CD8+ T-cell infiltration in gastric cancer
发表年份：2025 来源杂志：Frontiers in Immunology

86. Scalable Matrigel-Free Suspension Culture for Generating High-Quality Human Liver Ductal Organoids
发表年份：2025 来源杂志：CELL PROLIFERATION

87. Preclinical Development and a Case Report of a Nanobody-Based CLDN18.2 CAR-T IMC002 with Reduced On-Target Off-Tumor Toxicity
发表年份：2025 来源杂志：MOLECULAR CANCER THERAPEUTICS

88. Optimization of a Novel 2 + 2 BCMA × CD3 Bispecific Antibody for Minimized Cytokine Release and Potent Efficacy
发表年份：2025 来源杂志：MOLECULAR CANCER THERAPEUTICS

89. Targeting CHEK1: Ginsenosides-Rh2 and Cu2O@G-Rh2 nanoparticles in thyroid cancer
发表年份：2025 来源杂志：CELL BIOLOGY AND TOXICOLOGY

90. Targeted delivery of circPDHK1 siRNA via aptamer functionalized lipid nanoparticles inhibits ccRCC growth and migration
发表年份：2025 来源杂志：INTERNATIONAL JOURNAL OF PHARMACEUTICS

91. mRNA-laden lipid nanoparticle-enabled humanized CD19 CAR-T-cell engineering for the eradication of leukaemic cells
发表年份：2025 来源杂志：BRITISH JOURNAL OF HAEMATOLOGY

92. In vivo RNA-seq and infection model reveal the different infection and immune characteristics of B. pertussis strains in China
发表年份：2025 来源杂志：Frontiers in Cellular and Infection Microbiology

93. Cbl-b inhibition improves manufacturing efficiency and antitumoral efficacy of anti-CD19 CAR-T cells
发表年份：2025 来源杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

94. ASF1B promotes gastric cancer progression by modulating H2AC20 and activating PI3K/AKT and ERK1/2 pathways
发表年份：2025 来源杂志：Frontiers in Pharmacology

95. NVP-2, in combination with Orlistat, represents a promising therapeutic strategy for acute myeloid leukemia
发表年份：2025 来源杂志：CANCER BIOLOGY & THERAPY

96. Motor neuron and pancreas homeobox 1 (MNX1) suppresses Triple Negative Breast Cancer (TNBC) cell phagocytosis by macrophage through CD24 signaling
发表年份：2025 来源杂志：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

97. CD9 antibody enhances the anti-leukemia efficacy of γδT cells in adult B cell acute lymphoblastic leukemia
发表年份：2025 来源杂志：iScience

98. Demethylzeylasteral alleviates myeloid leukemia through PERK/eIF2α/ATF4/CHOP-mediated cell apoptosis
发表年份：2025 来源杂志：Translational Cancer Research

99. Clinical functional proteomics of intercellular signalling in pancreatic cancer
发表年份：2024 来源杂志：NATURE

100. Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
发表年份：2024 来源杂志：CANCER CELL

101. Lyophilized lymph nodes for improved delivery of chimeric antigen receptor T cells
发表年份：2024 来源杂志：NATURE MATERIALS

102. An oncolytic virus–T cell chimera for cancer immunotherapy
发表年份：2024 来源杂志：NATURE BIOTECHNOLOGY

103. The N6-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
发表年份：2024 来源杂志：Cancer Discovery

104. Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
发表年份：2024 来源杂志：Cell Metabolism

105. Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
发表年份：2024 来源杂志：Cell Metabolism

106. A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway
发表年份：2024 来源杂志：Molecular Cancer

107. Photo-metallo-immunotherapy: Fabricating Chromium-Based Nanocomposites to Enhance CAR-T Cell Infiltration and Cytotoxicity against Solid Tumors
发表年份：2024 来源杂志：ADVANCED MATERIALS

108. An Oral PROTAC Targeting HPK1 Degradation Potentiates Anti-Solid Tumor Immunity
发表年份：2024 来源杂志：ADVANCED MATERIALS

109. Enhanced engraftment of human haematopoietic stem cells via mechanical remodelling mediated by the corticotropin-releasing hormone
发表年份：2024 来源杂志：Nature Biomedical Engineering

110. Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice
发表年份：2024 来源杂志：Cell Stem Cell

111. FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity
发表年份：2024 来源杂志：Nature Communications

112. Acetylation-dependent regulation of core spliceosome modulates hepatocellular carcinoma cassette exons and sensitivity to PARP inhibitors
发表年份：2024 来源杂志：Nature Communications

113. PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma
发表年份：2024 来源杂志：Nature Communications

114. Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy
发表年份：2024 来源杂志：Nature Communications

115. Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice
发表年份：2024 来源杂志：Nature Communications

116. Specific surface-modified iron oxide nanoparticles trigger complement-dependent innate and adaptive antileukaemia immunity
发表年份：2024 来源杂志：Nature Communications

117. Succinate dehydrogenase deficiency-driven succinate accumulation induces drug resistance in acute myeloid leukemia via ubiquitin-cullin regulation
发表年份：2024 来源杂志：Nature Communications

118. Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies
发表年份：2024 来源杂志：Nature Communications

119. ATP6V1D drives hepatocellular carcinoma stemness and progression via both lysosome acidification-dependent and -independent mechanisms
发表年份：2024 来源杂志：Autophagy

120. Protein Kinase STK24 Promotes Tumor Immune Evasion via the AKT-PD-L1 Axis
发表年份：2024 来源杂志：Advanced Science

121. Kidney Organoid Modeling of WT1 Mutations Reveals Key Regulatory Paths Underlying Podocyte Development
发表年份：2024 来源杂志：Advanced Science

122. SIN3B Loss Heats up Cold Tumor Microenvironment to Boost Immunotherapy in Pancreatic Cancer
发表年份：2024 来源杂志：Advanced Science

123. SKAP1 Expression in Cancer Cells Enhances Colon Tumor Growth and Impairs Cytotoxic Immunity by Promoting Neutrophil Extracellular Trap Formation via the NFATc1/CXCL8 Axis
发表年份：2024 来源杂志：Advanced Science

124. A pan-KRAS degrader for the treatment of KRAS-mutant cancers
发表年份：2024 来源杂志：Cell Discovery

125. ADAR1 is required for acute myeloid leukemia cell survival by modulating post-transcriptional Wnt signaling through impairing miRNA biogenesis
发表年份：2024 来源杂志：LEUKEMIA

126. Anagrelide and idarubicin combination induces GSDME-mediated pyroptosis as a potential therapy for high-PDE3A acute myeloid leukemia
发表年份：2024 来源杂志：LEUKEMIA

127. Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
发表年份：2024 来源杂志：CANCER RESEARCH

128. Targeting SHCBP1 Inhibits Tumor Progression by Restoring Ciliogenesis in Ductal Carcinoma
发表年份：2024 来源杂志：CANCER RESEARCH

129. Adhesion GPCR ADGRE2 Maintains Proteostasis to Promote Progression in Acute Myeloid Leukemia
发表年份：2024 来源杂志：CANCER RESEARCH

130. PRDM16 Induces Methylation of FLT3 to Promote FLT3-ITD Signaling and Leukemia Progression
发表年份：2024 来源杂志：CANCER RESEARCH

131. HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy
发表年份：2024 来源杂志：Theranostics

132. Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy responses to anti-α4β7-integrin in Crohn’s disease
发表年份：2024 来源杂志：Gut Microbes

133. Venetoclax acts as an immunometabolic modulator to potentiate adoptive NK cell immunotherapy against leukemia
发表年份：2024 来源杂志：Cell Reports Medicine

134. Enhancer looping protein LDB1 modulates MYB expression in T-ALL cell lines in vitro by cooperating with master transcription factors
发表年份：2024 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

135. Integrated stress response activation induced by usnic acid alleviates BCL-2 inhibitor ABT-199 resistance in acute myeloid leukemia
发表年份：2024 来源杂志：Journal of Advanced Research

136. Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies
发表年份：2024 来源杂志：Journal of Advanced Research

137. Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia
发表年份：2024 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

138. LILRB4 on multiple myeloma cells promotes bone lesion by p-SHP2/NF-κB/RELT signal pathway
发表年份：2024 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

139. USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα
发表年份：2024 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

140. iPSC-derived NK cells with site-specific integration of CAR19 and IL24 at the multi-copy rDNA locus enhanced antitumor activity and proliferation
发表年份：2024 来源杂志：MedComm

141. Glutathione-depleting Liposome Adjuvant for Augmenting the Efficacy of a Glutathione Covalent Inhibitor Oridonin for Acute Myeloid Leukemia Therapy
发表年份：2024 来源杂志：JOURNAL OF NANOBIOTECHNOLOGY

142. RCAd-LTH-shPD-L1, a double-gene recombinant oncolytic adenovirus with enhanced antitumor immunity, increases lymphocyte infiltration and reshapes the tumor microenvironment
发表年份：2024 来源杂志：Journal for ImmunoTherapy of Cancer

143. ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis
发表年份：2024 来源杂志：Journal for ImmunoTherapy of Cancer

144. ImmunoPET imaging of LAG-3 expression in tumor microenvironment with 68Ga-labelled cyclic peptides tracers: from bench to bedside
发表年份：2024 来源杂志：Journal for ImmunoTherapy of Cancer

145. Engineered oncolytic virus expressing B7H3-targeting BiTE enhances antitumor T-cell immune response
发表年份：2024 来源杂志：Journal for ImmunoTherapy of Cancer

146. Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
发表年份：2024 来源杂志：EMBO JOURNAL

147. Ningetinib, a novel FLT3 inhibitor, overcomes secondary drug resistance in acute myeloid leukemia
发表年份：2024 来源杂志：Cell Communication and Signaling

148. KMT2D mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-induced regulatory T cell trafficking via FBXW7-NOTCH-MYC/TGF-β1 axis
发表年份：2024 来源杂志：International Journal of Biological Sciences

149. The interaction between UBR7 and PRMT5 drives PDAC resistance to gemcitabine by regulating glycolysis and immune microenvironment
发表年份：2024 来源杂志：Cell Death & Disease

150. A novel LGALS1-depended and immune-associated fatty acid metabolism risk model in acute myeloid leukemia stem cells
发表年份：2024 来源杂志：Cell Death & Disease

151. EZH2 promotes B-cell autoimmunity in primary Sjogren's syndrome via METTL3-mediated m6A modification
发表年份：2024 来源杂志：JOURNAL OF AUTOIMMUNITY

152. Connexin 25 maintains self-renewal and functions of airway basal cells for airway regeneration
发表年份：2024 来源杂志：Stem Cell Research & Therapy

153. Human umbilical cord mesenchymal stem cell-based gene therapy for hemophilia B using scAAV-DJ/8-LP1-hFIXco transduction
发表年份：2024 来源杂志：Stem Cell Research & Therapy

154. Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer
发表年份：2024 来源杂志：BIOMEDICINE & PHARMACOTHERAPY

155. IGSF9 promotes tumor invasion and metastasis through GSK-3β/β-catenin mediated EMT in lung cancer
发表年份：2024 来源杂志：NEOPLASIA

156. TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway
发表年份：2024 来源杂志：Journal of Translational Medicine

157. IMT030122, A novel engineered EpCAM/CD3/4-1BB tri-specific antibody, enhances T-cell recruitment and demonstrates anti-tumor activity in mouse models of colorectal cancer
发表年份：2024 来源杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

158. Oncolytic virus encoding 4-1BBL and IL15 enhances the efficacy of tumor-infiltrating lymphocyte adoptive therapy in HCC
发表年份：2024 来源杂志：CANCER GENE THERAPY

159. ARID5A stabilizes Indoleamine 2,3-dioxygenase expression and enhances CAR T cell exhaustion in colorectal cancer
发表年份：2024 来源杂志：Translational Oncology

160. Effective in vivo reactivation of HIV-1 latency reservoir via oral administration of EK-16A-SNEDDS
发表年份：2024 来源杂志：EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

161. Single-cell RNA-sequencing reveals a profound immune cell response in human cytomegalovirus-infected humanized mice
发表年份：2024 来源杂志：VIROLOGICA SINICA

162. Generation of self-renewing neuromesodermal progenitors with neuronal and skeletal muscle bipotential from human embryonic stem cells
发表年份：2024 来源杂志：Cell Reports Methods

163. PLA2G2D promotes immune escape in non-small cell lung cancer by regulating T cell immune function through PD-L1-expressing extracellular vesicles
发表年份：2024 来源杂志：SCANDINAVIAN JOURNAL OF IMMUNOLOGY

164. Targeting CD47 and Angiogenesis Demonstrates Effective Anti-Tumor Effect in Bladder Cancer
发表年份：2024 来源杂志：Biomedicines

165. Discovery of Phenylpyrazole Derivatives as a New Class of Selective Inhibitors of MCL-1 with Antitumor Activity
发表年份：2024 来源杂志：ACS Omega

166. FYB1-targeted modulation of CAPG promotes AML progression
发表年份：2024 来源杂志：MOLECULAR AND CELLULAR BIOCHEMISTRY

167. The DHODH inhibitor teriflunomide impedes cell proliferation and enhances chemosensitivity to daunorubicin (DNR) in T-cell acute lymphoblastic leukemia
发表年份：2024 来源杂志：ANNALS OF HEMATOLOGY

168. PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome
发表年份：2024 来源杂志：DNA AND CELL BIOLOGY

169. Regional delivery of mesothelin-targeted chimeric antigen receptor T-cell effectively and safely targets colorectal cancer liver metastases in mice
发表年份：2024 来源杂志：Journal of Gastrointestinal Oncology

170. Restoring T and B cell generation in X-linked severe combined immunodeficiency mice through hematopoietic stem cells adenine base editing
发表年份：2024 来源杂志：MOLECULAR THERAPY

171. Mid1 promotes synovitis in rheumatoid arthritis via ubiquitin-dependent post-translational modification
发表年份：2024 来源杂志：PHARMACOLOGICAL RESEARCH

172. miR-590-3p Overexpression Improves the Efficacy of hiPSC-CMs for Myocardial Repair
发表年份：2024 来源杂志：JACC-Basic to Translational Science

173. Cisplatin-induced Pyroptosis Enhances the Efficacy of PD-L1 Inhibitor in Small-Cell Lung Cancer via GSDME/IL12/CD4Tem Axis
发表年份：2024 来源杂志：International Journal of Biological Sciences

174. LncRNA ZNF674-AS1 drives cell growth and inhibits cisplatin-induced pyroptosis via up-regulating CA9 in neuroblastoma
发表年份：2024 来源杂志：Cell Death & Disease

175. Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation
发表年份：2024 来源杂志：Cell Death & Disease

176. Small extracellular vesicle piR-hsa-30937 derived from pancreatic neuroendocrine neoplasms upregulates CD276 in macrophages to promote immune evasion
发表年份：2024 来源杂志：Cancer Immunology Research

177. Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
发表年份：2024 来源杂志：Cell Reports

178. Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation
发表年份：2024 来源杂志：Stem Cell Research & Therapy

179. Dehydrocostus lactone alleviates irinotecan-induced intestinal mucositis by blocking TLR4/MD2 complex formation
发表年份：2024 来源杂志：PHYTOMEDICINE

180. Lactate/GPR81 recruits regulatory T cells by modulating CX3CL1 to promote immune resistance in a highly glycolytic gastric cancer
发表年份：2024 来源杂志：OncoImmunology

181. PHE1-based IgG-like antibody platform provides a novel strategy for enhanced T-cell immunotherapy
发表年份：2024 来源杂志：Frontiers in Immunology

182. INPP4B suppresses HER2-induced mesenchymal transition in HER2+ breast cancer and enhances sensitivity to Lapatinib
发表年份：2024 来源杂志：BIOCHEMICAL PHARMACOLOGY

183. The CDK4/6 inhibitor Palbociclib synergizes with ATRA to induce differentiation in AML
发表年份：2024 来源杂志：MOLECULAR CANCER THERAPEUTICS

184. TYM-3-98, a novel selective inhibitor of PI3Kδ, demonstrates promising preclinical antitumor activity in B-cell lymphomas
发表年份：2024 来源杂志：LIFE SCIENCES

185. FAM120A deficiency improves resistance to cisplatin in gastric cancer by promoting ferroptosis
发表年份：2024 来源杂志：Communications Biology

186. HDAC inhibitors target IRS4 to enhance anti‑AR therapy in AR‑positive triple‑negative breast cancer
发表年份：2024 来源杂志：INTERNATIONAL JOURNAL OF ONCOLOGY

187. Preclinical evaluation of the theranostic potential of 89Zr/177Lu-labeled anti-TROP-2 antibody in triple-negative breast cancer model
发表年份：2024 来源杂志：EJNMMI Radiopharmacy and Chemistry

188. PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome
发表年份：2024 来源杂志：DNA AND CELL BIOLOGY

189. Exosome-derived circCCAR1 promotes CD8+T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
发表年份：2023-03-18 来源杂志：Molecular Cancer

190. A novel antidiuretic hormone governs tumour-induced renal dysfunction
发表年份：2023 来源杂志：NATURE

191. Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals
发表年份：2023 来源杂志：CELL

192. Imatinib blocks tyrosine phosphorylation of Smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia
发表年份：2023 来源杂志：Signal Transduction and Targeted Therapy

193. Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
发表年份：2023 来源杂志：Molecular Cancer

194. Tumors evade immune cytotoxicity by altering the surface topology of NK cells
发表年份：2023 来源杂志：NATURE IMMUNOLOGY

195. Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress
发表年份：2023 来源杂志：GASTROENTEROLOGY

196. Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
发表年份：2023 来源杂志：Cell Metabolism

197. The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation
发表年份：2023 来源杂志：Cellular & Molecular Immunology

198. STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
发表年份：2023 来源杂志：NATURE CELL BIOLOGY

199. Cyclosporine A-resistant CAR-T cells mediate antitumour immunity in the presence of allogeneic cells
发表年份：2023 来源杂志：Nature Communications

200. SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activity
发表年份：2023 来源杂志：Nature Communications

201. Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia
发表年份：2023 来源杂志：Nature Communications

202. Sequence-based drug design as a concept in computational drug design
发表年份：2023 来源杂志：Nature Communications

203. TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models
发表年份：2023 来源杂志：Nature Communications

204. Low level of ARID1A contributes to adaptive immune resistance and sensitizes triple-negative breast cancer to immune checkpoint inhibitors
发表年份：2023 来源杂志：Cancer Communications

205. Enhancement of CAR-T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins
发表年份：2023 来源杂志：Cancer Communications

206. Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling
发表年份：2023 来源杂志：JOURNAL OF CLINICAL INVESTIGATION

207. Cell autonomous expression of BCL6 is required to maintain lineage identity of mouse CCR6+ ILC3s
发表年份：2023 来源杂志：JOURNAL OF EXPERIMENTAL MEDICINE

208. CAR-Aptamers Enable Traceless Enrichment and Monitoring of CAR-Positive Cells and Overcome Tumor Immune Escape
发表年份：2023 来源杂志：Advanced Science

209. NIRF/PET imaging of γδ T cells via metabolic glycoengineering and bioorthogonal labeling
发表年份：2023 来源杂志：CHEMICAL ENGINEERING JOURNAL

210. Novel Human Meningioma Organoids Recapitulate the Aggressiveness of the Initiating Cell Subpopulations Identified by ScRNA-Seq
发表年份：2023 来源杂志：Advanced Science

211. Targeted therapy of central nervous system acute lymphoblastic leukemia with an integrin α6-targeted self-assembling proapoptotic nanopeptide
发表年份：2023 来源杂志：Engineering

212. Gut microbiota-related bile acid metabolism-FXR/TGR5 axis impacts the response to anti-α4β7-integrin therapy in humanized mice with colitis
发表年份：2023 来源杂志：Gut Microbes

213. Transcription factor Nkx2-3 maintains the self-renewal of hematopoietic stem cells by regulating mitophagy
发表年份：2023 来源杂志：LEUKEMIA

214. TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability
发表年份：2023 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

215. Targeting the Immunoglobulin IGSF9 Enhances Antitumor T-cell Activity and Sensitivity to Anti–PD-1 Immunotherapy
发表年份：2023 来源杂志：CANCER RESEARCH

216. PICH activates Cyclin A1 transcription to drive S-phase progression and chemoresistance in gastric cancer.
发表年份：2023 来源杂志：CANCER RESEARCH

217. Faecalibacterium prausnitzii abrogates intestinal toxicity and promotes tumor immunity to increase the efficacy of dual CTLA-4 and PD-1 checkpoint blockade
发表年份：2023 来源杂志：CANCER RESEARCH

218. Targeted glycan degradation potentiates cellular immunotherapy for solid tumors
发表年份：2023 来源杂志：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

219. Sitravatinib as a potent FLT3 inhibitor can overcome gilteritinib resistance in acute myeloid leukemia
发表年份：2023 来源杂志：Biomarker Research

220. TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer
发表年份：2023 来源杂志：JOURNAL OF NANOBIOTECHNOLOGY

221. DNAJC10 maintains survival and self-renewal of leukemia stem cells through PERK branch of the unfolded protein response
发表年份：2023 来源杂志：HAEMATOLOGICA

222. Tissue factor overexpression in triple-negative breast cancer promotes immune evasion by impeding T-cell infiltration and effector function
发表年份：2023 来源杂志：CANCER LETTERS

223. Covalent targeting the LAS1-NOL9 axis for selective treatment in NPM1 mutant acute myeloid leukemia
发表年份：2023 来源杂志：PHARMACOLOGICAL RESEARCH

224. PARP inhibitor exerts an anti-tumor effect via LMO2 and synergizes with cisplatin in natural killer/T cell lymphoma
发表年份：2023 来源杂志：BMC Medicine

225. Alternative splicing of HOXB-AS3 underlie the promoting effect of nuclear m6A reader YTHDC1 on the self-renewal of leukemic stem cells in acute myeloid leukemia
发表年份：2023 来源杂志：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

226. TGF-β blocking combined with photothermal therapy promote tumor targeted migration and long-term antitumor activity of CAR-T cells
发表年份：2023 来源杂志：Materials Today Bio

227. Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
发表年份：2023 来源杂志：ACTA PHARMACOLOGICA SINICA

228. Hypoimmunogenic human pluripotent stem cells are valid cell sources for cell therapeutics with normal self-renewal and multilineage differentiation capacity
发表年份：2023 来源杂志：Stem Cell Research & Therapy

229. Bispecific NK-cell engager targeting BCMA elicits stronger antitumor effects and produces less proinflammatory cytokines than T-cell engager
发表年份：2023 来源杂志：Frontiers in Immunology

230. SIGLEC10+ macrophages drive gastric cancer progression by suppressing CD8+ T cell function
发表年份：2023 来源杂志：CANCER IMMUNOLOGY IMMUNOTHERAPY

231. Chemokine Receptors CCR6 and PD1 Blocking scFv E27 Enhances Anti-EGFR CAR-T Therapeutic Efficacy in a Preclinical Model of Human Non-Small Cell Lung Carcinoma
发表年份：2023 来源杂志：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

232. CCL17 acts as an antitumor chemokine in micromilieu‐driven immune skewing
发表年份：2023 来源杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

233. Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Env+ cells in vivo
发表年份：2023 来源杂志：VIROLOGICA SINICA

234. Bruton tyrosine kinase inhibitors preserve anti-CD19 chimeric antigen receptor T-cell functionality and reprogram tumor micro-environment in B-cell lymphoma
发表年份：2023 来源杂志：CYTOTHERAPY

235. A second-generation CD38-CAR-T cell for the treatment of multiple myeloma
发表年份：2023 来源杂志：Cancer Medicine

236. Oxymatrine boosts hematopoietic regeneration by modulating MAPK/ERK phosphorylation after irradiation-induced hematopoietic injury
发表年份：2023 来源杂志：EXPERIMENTAL CELL RESEARCH

237. PD-L1 ImmunoPET on the basis of Avidin/Biotin pre-targeted cancer imaging
发表年份：2023 来源杂志：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

238. T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
发表年份：2022-07-26 来源杂志：nature communications

239. A Chimeric Conjugate of Antibody and Programmable DNA Nanoassembly Smartly Activates T cell for Precise Cancer Cell Targeting
发表年份：2022-06-24 来源杂志：A Journal of the Gesellschaft Deutscher Chemiker

240. BSA-AIE Nanoparticles with Boosted ROS Generation for Immunogenic Cell Death Immunotherapy of Multiple Myeloma
发表年份：2022 来源杂志：ADVANCED MATERIALS

241. Synthetic libraries of immune cells displaying a diverse repertoire of chimaeric antigen receptors as a potent cancer immunotherapy
发表年份：2022 来源杂志：Nature Biomedical Engineering

242. T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
发表年份：2022 来源杂志：Nature Communications

243. Malfunction of airway basal stem cells plays a crucial role in pathophysiology of tracheobronchopathia osteoplastica
发表年份：2022 来源杂志：Nature Communications

244. Modeling Human Thyroid Development by Fetal Tissue-Derived Organoid Culture
发表年份：2022 来源杂志：Advanced Science

245. Inhibition of Calcium Signaling Prevents Exhaustion and Enhances Anti-Leukemia Efficacy of CAR-T Cells via SOCE-Calcineurin-NFAT and Glycolysis Pathways
发表年份：2022 来源杂志：Advanced Science

246. Nano-Biohybrid DNA Engager That Reprograms the T-Cell Receptor
发表年份：2022 来源杂志：Journal of the American Chemical Society

247. Therapeutic strategies targeting uPAR potentiate anti–PD-1 efficacy in diffuse-type gastric cancer
发表年份：2022 来源杂志：Science Advances

248. Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia
发表年份：2022 来源杂志：Acta Pharmaceutica Sinica B

249. An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ
发表年份：2022 来源杂志：MOLECULAR THERAPY

250. Single-cell ATAC-seq maps the comprehensive and dynamic chromatin accessibility landscape of CAR-T cell dysfunction
发表年份：2022 来源杂志：LEUKEMIA

251. FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer
发表年份：2022 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

252. Deneddylation of PML/RARα reconstructs functional PML nuclear bodies via orchestrating phase separation to eradicate APL
发表年份：2022 来源杂志：CELL DEATH AND DIFFERENTIATION

253. Visualizing γδ T cells by very late antigen-4-targeted positron emission tomography
发表年份：2022 来源杂志：EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

254. Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2
发表年份：2022 来源杂志：Cell Reports

255. Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations
发表年份：2022 来源杂志：Cell Reports

256. Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma
发表年份：2022 来源杂志：Cell Death & Disease

257. Stathmin 1 is a biomarker for diagnosis of microvascular invasion to predict prognosis of early hepatocellular carcinoma
发表年份：2022 来源杂志：Cell Death & Disease

258. LncSIK1 enhanced the sensitivity of AML cells to retinoic acid by the E2F1/autophagy pathway
发表年份：2022 来源杂志：CELL PROLIFERATION

259. Gene therapy with B-cell maturation antigen/CD3 bispecific antibody encoding plasmid DNA for treating multiple myeloma
发表年份：2022 来源杂志：BRITISH JOURNAL OF HAEMATOLOGY

260. Anti-c-MET Fab-Grb2-Gab1 Fusion Protein-Mediated Interference of c-MET Signaling Pathway Induces Methuosis in Tumor Cells
发表年份：2022 来源杂志：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

261. SLC35B4 Stabilizes c-MYC Protein by O-GlcNAcylation in HCC
发表年份：2022 来源杂志：Frontiers in Pharmacology

262. Cathepsin L promotes chemresistance to neuroblastoma by modulating serglycin
发表年份：2022 来源杂志：Frontiers in Pharmacology

263. Large-cohort humanized NPI mice reconstituted with CD34+ hematopoietic stem cells are feasible for evaluating preclinical cancer immunotherapy
发表年份：2022 来源杂志：FASEB JOURNAL

264. Preclinical Assessment of MEK Inhibitors for Malignant Peripheral Nerve Sheath Tumors Reveals Differences in Efficacy and Adaptive Response
发表年份：2022 来源杂志：Frontiers in Oncology

265. ABCC6 Knockdown Fuels Cell Proliferation by Regulating PPARα in Hepatocellular Carcinoma
发表年份：2022 来源杂志：Frontiers in Oncology

266. LncRNA SNHG3 enhances BMI1 mRNA stability by binding and regulating c-MYC: Implications for the carcinogenic role of SNHG3 in bladder cancer
发表年份：2022 来源杂志：Cancer Medicine

267. Liver type 1 innate lymphoid cells develop locally via an interferon-γ–dependent loop
发表年份：2021 来源杂志：SCIENCE

268. A chimeric antigen receptor with antigen-independent OX40 signaling mediates potent antitumor activity
发表年份：2021 来源杂志：Science Translational Medicine

269. The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
发表年份：2021 来源杂志：MOLECULAR CELL

270. CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma through 5-lipoxygenase
发表年份：2021 来源杂志：HEPATOLOGY

271. DMDRMR-Mediated Regulation of m6A-Modified CDK4 by m6A Reader IGF2BP3 Drives ccRCC Progression
发表年份：2021 来源杂志：CANCER RESEARCH

272. Fresh Tissue Multi-omics Profiling Reveals Immune Classification and Suggests Immunotherapy Candidates for Conventional Chondrosarcoma
发表年份：2021 来源杂志：CLINICAL CANCER RESEARCH

273. WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit
发表年份：2021 来源杂志：Acta Pharmaceutica Sinica B

274. TIGIT-Fc Promotes Antitumor Immunity
发表年份：2021 来源杂志：Cancer Immunology Research

275. FOXP1 drives osteosarcoma development by repressing P21 and RB transcription downstream of P53
发表年份：2021 来源杂志：ONCOGENE

276. Chemokine Receptor CCR2b Enhanced Anti-tumor Function of Chimeric Antigen Receptor T Cells Targeting Mesothelin in a Non-small-cell Lung Carcinoma Model
发表年份：2021 来源杂志：Frontiers in Immunology

277. Enhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cells
发表年份：2021 来源杂志：Stem Cell Research & Therapy

278. Engineering mesenchymal stromal cells with neutralizing and anti-inflammatory capability against SARS-CoV-2 infection
发表年份：2021 来源杂志：Molecular Therapy-Methods & Clinical Development

279. Bcl-2 Enhances Chimeric Antigen Receptor T Cell Persistence by Reducing Activation-Induced Apoptosis
发表年份：2021 来源杂志：Cancers

280. A novel and effective approach to generate germline-like monoclonal antibodies by integration of phage and mammalian cell display platforms
发表年份：2021 来源杂志：ACTA PHARMACOLOGICA SINICA

281. Establishment of Functional Liver Spheroids From Human Hepatocyte-Derived Liver Progenitor-Like Cells for Cell Therapy
发表年份：2021 来源杂志：Frontiers in Bioengineering and Biotechnology

282. Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy
发表年份：2021 来源杂志：Frontiers in Pharmacology

283. RXR Negatively Regulates Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem and Progenitor Cells
发表年份：2021 来源杂志：Stem Cell Reviews and Reports

284. Demethyleneberberine induces cell cycle arrest and cellular senescence of NSCLC cells via c-Myc/HIF-1α pathway
发表年份：2021 来源杂志：PHYTOMEDICINE

285. CoFe2O4-Quantum Dots for Synergistic Photothermal/Photodynamic Therapy of Non-small-Cell Lung Cancer Via Triggering Apoptosis by Regulating PI3K/AKT Pathway
发表年份：2021 来源杂志：Nanoscale Research Letters

286. NGF nanoparticles enhance the potency of transplanted human umbilical cord mesenchymal stem cells for myocardial repair
发表年份：2021 来源杂志：AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

287. Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model: the first pre-clinical study for safety and efficacy in China
发表年份：2021 来源杂志：Annals of Translational Medicine

288. Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics
发表年份：2020 来源杂志：CELL

289. SH3RF3 promotes breast cancer stem-like properties via JNK activation and PTX3 upregulation
发表年份：2020 来源杂志：Nature Communications

290. Generation of hypoimmunogenic human pluripotent stem cells via expression of membrane-bound and secreted β2m-HLA-G fusion proteins
发表年份：2020 来源杂志：STEM CELLS

291. 4-1BB Signaling Boosts the Anti-Tumor Activity of CD28-Incorporated 2nd Generation Chimeric Antigen Receptor-Modified T Cells
发表年份：2020 来源杂志：Frontiers in Immunology

292. Arming Anti-EGFRvIII CAR-T With TGFβ Trap Improves Antitumor Efficacy in Glioma Mouse Models
发表年份：2020 来源杂志：Frontiers in Oncology

293. The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation
发表年份：2020 来源杂志：Aging-US

294. Lgr5 maintains stemness and regulates cell property in nasopharyngeal carcinoma through Wnt/β-catenin signaling pathway
发表年份：2020 来源杂志：Stem Cell Research

295. Peptide Self-Assembly Nanoparticles Loaded with Panobinostat to Activate Latent Human Immunodeficiency Virus
发表年份：2019-05-01 来源杂志：J Biomed Nanotechnol