hCD19

Fig.1 Expression characterization of hCD19 on B cells in blood in hCD19 knockin mice.

Fig.2 Expression characterization of hCD19 on B cells in spleen in hCD19 knockin mice.

Fig.3 Expression characterization of hCD19 on B cells in thymus in hCD19 knockin mice.

Fig.4 Body weight and ratios of spleen, thymus and MLN to body weight of 8-week-old hCD19 knockin mice. (n=6 for all groups, Mean±SEM, Unpaired t-test, *P<0.05, **P<0.01).

Abbr. HO, homozygous; WT, wild type; MLN, mesenteric lymph nodes.

Table 1. Blood routine examination of hCD19 knockin mice. Values are expressed as mean±SEM.

Abbr. HO, homozygous; WT, wild type.

Table 2. Biochemical test of serum from hCD19 knockin mice. Values are expressed as mean±SEM.

Abbr. HO, homozygous; WT, wild type.

Fig.5 Blood biochemical detection of 8-week-old hCD19 knockin mice. (n=6 for all groups, Mean±SEM).

Abbr. HO, homozygous; WT, wild type.

Fig.6 Detection of myeloid cell subsets in the blood of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

Fig.7 Detection of lymphocyte subsets in the blood of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

Fig.8 Detection of myeloid cell subsets in the spleen of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

Fig.9 Detection of lymphocyte subsets in the spleen of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).

Abbr.  WT, wild type; HO, homozygous.

Fig.10 Pathological analysis of hCD19 knockin mice by H＆E staining. 

There were no obvious pathological changes in these tissues. (n=3, 8-week-old)