hAPOC3
品系全名
C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
目录号
NM-HU-225050
品系状态
活体
基因信息
基因名
Apoc3
品系描述
利用同源重组，将小鼠Apoc3基因进行人源化修饰。
*使用本品系发表的文献需注明: hAPOC3 mice (Cat. NO. NM-HU-225050) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of APOC3 expression in liver by RT-PCR.
Wild type: only one band at 196 bp with primers F1/R1(mApoc3); Homozygous: only one band at 219 bp with primers F2/R2(hAPOC3). Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Detection of species-specific APOC3 expression in serum by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
Fig3. Monitoring of blood lipids levels in hAPOC3 mice (n=3 female and 3 male).
Abbr. Hom, homozygous; WT, wild type.
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