Sftpc-IRES-CreERT2

利用CRISPR基因编辑技术，将IRES-CreERT2敲入到小鼠Sftpc基因3'UTR中，他莫昔芬诱导型Cre重组酶CreERT2受内源Sftpc基因启动子驱动。诱导后，在II型肺泡细胞中表达Cre活性。 *该品系CreERT2有泄露情况（详见验证数据），请根据研究目的进行选择。

Fig1. Cre mediated recombination in lung of Sftpc^CreERT2/+;Rosa26^tdTomato/+ mouse.

Fig2. Detection of tdTomato(red) in various tissues of Sftpc^CreERT2/+;Rosa26^tdTomato/+ mouse. Expression tissues include: lung epithelial cells, testis interstitial cells, salivary glands, muscles. Tissues that unexpressed include brain, spinal cord, retina, heart, liver, brown fat, thymus, kidney, pancreas, large and small intestine, spleen, and skin.(2-months old, male) (For more detailed information please contact our technical advisor.)