Clec4f-2A-CreERT2
品系全名
C57BL/6Smoc-Clec4fem(2A-CreERT2)1Smoc
目录号
NM-KI-225083
品系状态
活体
基因信息
基因名
Clec4f
品系描述
验证数据

Fig1. CreERT2 mediated recombination in spinal cord of Clec4fCreERT2/+; Rosa26tdTomato/+ mouse.

Fig2. Co-localization of tdTomato-positive cells with Clec4f was observed in the livers of Clec4fCreERT2/+; Rosa26tdTomato/+ mouse.

Fig3. Detection of tdTomato(red) in various tissues of Clec4fCreERT2/+; Rosa26tdTomato/+ mouse.
Following tamoxifen induction, tissues expressing tdTomato included the liver, reproductive system and Lymph node.
Following tamoxifen induction, no significant fluorescence expression was observed in the brain, spleen, lungs, large intestine, small intestine, salivary glands, or prostate of the mice. (973-days old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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