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Models

为您找到相关结果约462个
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Mapk8-KO

品系名：C57BL/6Smoc-Mapk8em1Smoc
品系状态：胚胎冻存 | 目录号：NM-KO-190836

Exon 3 of Mapk8 gene was deleted to generate Mapk8 knockout mice.

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Fam220a-KO

品系名：C57BL/6Smoc-Fam220aem1Smoc
品系状态：胚胎冻存 | 目录号：NM-KO-190273

This Fam220a knockout mouse model was generated by knocking out the exon 2 region of the Fam220a.

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Hdac5-SA

品系名：C57BL/6Smoc-Hdac5em1Chr11:102197179A>CSmoc
品系状态：精子冻存 | 目录号：NM-KI-231786

These strains carry a Chr11:102197179A>C mutation of Hdac5 gene.

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Mki67-RSR-2A-Cre

品系名：C57BL/6-Mki67em(C-Rox-STOP-C-Rox-2A-Cre-WPRE-pA)Smoc
品系状态：精子冻存 | 目录号：NM-KI-220093

C-Rox-STOP-C-Rox-2A-Cre-WPRE-pA expression cassette was knocked into the Mki67 gene stop codon site.

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Srebf1c-Flox

品系名：C57BL/6Smoc-Srebf1em2(c-flox)Smoc
品系状态：精子冻存 | 目录号：NM-CKO-242219

These strains carry loxP sites flanking exon 1 of 207 transcipt of Srebf1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Srebf1 gene(Srebf1c isoform).

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Hdac4-SA/Hdac5-SA

品系名：C57BL/6Smoc-Hdac4em1Chr1:91947538A>THdac5em1Chr11:102197179A>CSmoc
品系状态：精子冻存 | 目录号：NM-XA-241541
验证数据：有

The Hdac4-SA(NM-KI-231785) was crossed with Hdac5-SA(NM-KI-231786) to generate Hdac4-Chr1:91947538A>T/Hdac5-Chr11:102197179A>C mice.

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NMG-Hc(NMG)

品系名：NOD.Cg-PrkdcscidIl2rgem1Hcem3(c.645InsTA)Smoc
品系状态：胚胎冻存 | 目录号：NM-NSG-012

These NMG mice carry a c.645InsTA mutation of Hc gene.

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R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomato

品系名：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
品系状态：胚胎冻存 | 目录号：NM-KI-18052

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.

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Fcgr2b-KO(3)

品系名：C57BL/6Smoc-Fcgr2bem1Smoc
品系状态：精子冻存 | 目录号：NM-KO-210279
验证数据：有

Fcgr2b-KO(3) mice (Stock No.NM-KO-210279）carry a knockout allele derived from the targeted deletion of exon 3-5.Fcgr2b-KO mice (Stock No.NM-KO-00130）carry a knockout allele derived from the targeted deletion of exon 3. Fcgr2b-KO(2) mice (NM-KO-191214） have been pulled from shelves for some reasons.

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H11-CAG-LSL-Myc

品系名：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
品系状态：活体 | 目录号：NM-KI-00039
验证数据：有

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

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