历年文献基因敲除小鼠_转基因小鼠定制

                            
                            Treatment of hemophilic arthropathy by immunomodulatory extracellular vesicle delivered by liposome hybrid nanoparticles
                        

产品名称：F8-KO

研究领域：罕见病; 脂质体

发表年份：2024 发表杂志：Bioactive Materials

                            
                            Microbiota regulates the TET1-mediated DNA hydroxymethylation program in innate lymphoid cell differentiation
                        

产品名称：Tet1-Flox

研究领域：其它;ILC亚群及其各自前体的DNA甲基化和羟甲基化的全基因组分布和动态

发表年份：2024 发表杂志：Nature Communications

                            
                            Targeting Rab7-Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy
                        

产品名称：Rab7-flox;Myh6-CreERT2

研究领域：代谢心血管;糖尿病性心肌病(DbCM)

发表年份：2024 发表杂志：Advanced Science

                            
                            Single-Cell Spatial Transcriptomics Unveils Platelet-Fueled Cycling Macrophages for Kidney Fibrosis
                        

产品名称：Thbs1-KO

研究领域：自身免疫及炎症;肾脏疾病

发表年份：2024 发表杂志：Advanced Science

                            
                            Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus
                        

产品名称：UNC93B1-V117L

研究领域：自身免疫及炎症;红斑狼疮

发表年份：2024 发表杂志：NATURE IMMUNOLOGY

                            
                            Single cell analyses reveal the PD-1 blockade response-related immune features in hepatocellular carcinoma
                        

产品名称：Trem2-KO

研究领域：肿瘤及肿瘤免疫;肝细胞癌

发表年份：2024 发表杂志：Theranostics

                            
                            ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity
                        

产品名称：Abcc1-KO

研究领域：其它;基因突变

发表年份：2024 发表杂志：Redox Biology

                            
                            Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
                        

产品名称：Lmna-Flox;Ncr1-2A-Cre;Rag2/Il2rg-KO;Nat8l-KO;Lmna-K542Q

研究领域：肿瘤及肿瘤免疫;乳腺癌

发表年份：2024 发表杂志：CANCER CELL

                            
                            FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity
                        

产品名称：M-NSG

研究领域：肿瘤及肿瘤免疫;鼻咽癌

发表年份：2024 发表杂志：Nature Communications

                            
                            FGD5 in basal cells induces CXCL14 secretion that initiates a feedback loop to promote murine mammary epithelial growth and differentiation
                        

产品名称：R26-CAG-LSL-Luc-tdTomato

研究领域：其它;乳腺的发育和稳态

发表年份：2024 发表杂志：DEVELOPMENTAL CELL

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Treatment of hemophilic arthropathy by immunomodulatory extracellular vesicle delivered by liposome hybrid nanoparticles

Microbiota regulates the TET1-mediated DNA hydroxymethylation program in innate lymphoid cell differentiation

Targeting Rab7-Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy

Single-Cell Spatial Transcriptomics Unveils Platelet-Fueled Cycling Macrophages for Kidney Fibrosis

Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus

Single cell analyses reveal the PD-1 blockade response-related immune features in hepatocellular carcinoma

ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity

Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity

FGD5 in basal cells induces CXCL14 secretion that initiates a feedback loop to promote murine mammary epithelial growth and differentiation

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