历年文献

HDAC3 Mediates Hippocampal Microglial Pyroptosis Via the STING/NLRP3 Pathway and Contributes To Cognitive Impairment in Sepsis-Associated Encephalopathy

模式生物:小鼠 产品与服务:Cx3cr1-Cre 研究领域:败血症相关脑病; 小胶质细胞

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1-KDM5C-IL6 Axis in ccRCC

模式生物:小鼠 产品与服务:Pbrm1-Flox; Vhl-Flox 研究领域:肾透明细胞癌; 肿瘤免疫逃逸

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome-Mediated Colitis and Mood Disorder

模式生物:小鼠 产品与服务:Cx3cr1-CreERT2 研究领域:NLRP3炎症小体; 慢性炎症性疾病

Transient mechanical activation of the Piezo1 channel facilitates ex vivo expansion of hematopoietic stem cells

模式生物:小鼠 产品与服务:Piezo1-Flox 研究领域:造血干细胞

Mesenchymal stromal cells counteract with age-related immune decline and enhance vaccine efficacy by modulating endogenous splenic marginal reticular cells in elderly models

模式生物:小鼠 产品与服务:Madcam1-T2A-tdTomato-P2A-CreERT2 研究领域:免疫; 脾脏微环境; 疫苗应答

Lipid-induced granules in hepatocytes alleviate liver fibrosis

模式生物:小鼠 产品与服务:Alb-Cre 研究领域:肝纤维化; 无膜细胞器;

N4BP1 acts as a potent negative regulator of IL-17 signaling by blocking the translation of Act1 mRNA

模式生物:小鼠 产品与服务:N4BP1-ko 研究领域:IL-17; 银屑病

Piezo1 knockdown activates PI3K/AKT and enhances SPP1 to drive M2 macrophage polarization and reduce cardiac inflammation

模式生物:小鼠 产品与服务:Piezo1-Flox; Lyz-Cre 研究领域:败血症; 感染性心脏功能障碍

Post-traumatic stress disorder impairs CD8+ T cell-dependent anti-tumor immune responses by downregulating thiamine

模式生物:小鼠 产品与服务:C57BL/6 研究领域:创伤后应激障碍; 肿瘤免疫

Calcium overload induced mitochondrial and lysosomal dysfunction is regulated by Tousled-like kinase in a-synucleinopathy

模式生物:小鼠 产品与服务:GluR1-Luc; TLK2-Flox; UBC-CreERT2 研究领域:帕金森病; 钙过载

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