hTHPO(M-NSG)

品系全名

NOD.Cg-PrkdcscidIl2rgem1Thpotm(hTHPO)Smoc

目录号

NM-HU-220429

品系状态

胚胎冻存

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基因信息

基因名
Thpo

品系描述

通过 hTHPO(NM-HU-2000062)与M-NSG小鼠回交后获得。

验证数据

image.png

Fig.1 Detection of THPO expression in adrenal and liver by RT-PCR. 

Wild type: only one band at 166 bp with primers F1/R1(mThpo);

Homozygous: only one band at 167 bp with primers F2/R2(hTHPO).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hTHPO expression in serum and liver homogenate by ELISA (male, 6-11wks).

Abbr. HO, Homozygous; WT, wild type.

Note. hTHPO(M-NSG) and M-NSG mice were i.p. injected with LPS. The Human Thrombopoietin ELISA Kit cross-reacted with mouse THPO and humanized THPO.

image.png

Fig.3 Detection of hTHPO expression in hTHPO(M-NSG) mice by WB. 

Abbr. M, marker; WT, wild type; PC, positive control, Hela cells.

Note. The anti-human THPO Antibody cross-reacted with mouse THPO and humanized THPO.


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