Drd2-KO

品系全名

C57BL/6JSmo-Drd2em1Smoc

目录号

NM-KO-190265

品系状态

精子冻存

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基因信息

基因名
Drd2

基因曾用名

D2R; Drd-2

NCBI ID

13489

MGI ID

94924

Ensembl ID

ENSMUSG00000032259

Pubmed

Drd2

人类同源基因

DRD2

品系描述

敲除Drd2基因的exon3区域，获得Drd2基因敲除小鼠模型。
应用领域：免疫相关

疾病预测

帕金森病
Parkinson's Disease

近似模型的表型

MGI:2675764

参考文献

Saiardi A, Borrelli E, Absence of dopaminergic control on melanotrophs leads to Cushing's-like syndrome in mice. Mol Endocrinol. 1998 Aug;12(8):1133-9

帕金森病
Parkinson's Disease

近似模型的表型

MGI:2675764

参考文献

Saiardi A, Borrelli E, Absence of dopaminergic control on melanotrophs leads to Cushing's-like syndrome in mice. Mol Endocrinol. 1998 Aug;12(8):1133-9

发表文献 1篇

1. Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection
发表年份：2020 来源杂志：Nature Communications

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