Ascl1-CreERT2

Fig. 1 CreERT2-mediated recombination in the hippocampus of Ascl1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse. TdTomato(red) expression can be detected in the dentate gyrus granule cell layer and molecular layer of Ascl1 ^{CreERT2 /+}; Rosa26^tdTomato/+ mouse after tamoxifen treatment. Some leakiness were detected in the molecular layer prior to tamoxifen exposure. 

Fig. 2 CreERT2-mediated recombination in the lateral ventricles of Ascl1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse. TdTomato(red) expression can be detected in the subventricular zone of Ascl1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse after tamoxifen treatment. 

Fig. 3 Detection of tdTomato(red) in various tissues of Ascl1^CreERT2/+; Rosa26^tdTomato/+ mice. CreERT2 mediated recombination can be detected in the hippocampus and lateral ventricles after tamoxifen treatment. Besides, tamoxifen-dependent cre recombinase expression can be also detected in some cells derived from thymus and the submucosa of the stomach and small intestine, except for submandibular gland, retina, lung, brown fat, kidney, muscle and spleen. (For more detailed information please contact our technical advisor.)