Krt5-IRES-CreERT2

Fig. 1 Detection of tdTomato (red) in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+  mouse. CreERT2-mediated recombination in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+ mouse. Some leakiness were detected in the epidermis and hair follicle prior to tamoxifen exposure.

Fig. 2 Detection of tdTomato (red) in various tissues of Krt5CreERT2/+; Rosa26tdTomato/+ mice. 

CreERT2-mediated recombination in the brown fat and submandibular gland can be induced by tamoxifen. Some leakiness were detected in the skin，eyes and testis prior to tamoxifen exposure.