B2m-KO(NMG)
品系全名
M-NSG-B2memSmoc
目录号
NM-NSG-002
品系状态
胚胎冻存
基因信息
基因名
B2M
品系描述
This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.
应用领域：immunodeficiency,immune system,transplantation research
*使用本品系发表的文献需注明: B2m-KO(NMG) mice (Cat. NO. NM-NSG-002) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig 1. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(NMG) mice.
Fig 2. Body weight growth curve of huPBMC-B2m-KO(NMG) mice.
Fig 3. Survival rate of huPBMC-B2m-KO(NMG) mice.
Fig 4. GvHD scores of huPBMC-B2m-KO(NMG) mice.
Fig 5. Percentage of hCD45-positive cells of huPBMC-B2m-KO(NMG) mice.
Fig 6. Flow analysis of peripheral blood lymphocyte subpopulations in the huPBMC-B2m-KO(NMG) mice.
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