hTSLP

品系全名

C57BL/6JSmo-Tslptm2(hTSLP)/Smoc

目录号

NM-HU-2000064

品系状态

胚胎冻存

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基因信息

基因名
TSLP

品系描述

通过同源重组,将小鼠Tslp基因进行人源化修饰。
应用领域:哮喘相关;药物筛选

验证数据

image.png

Fig.1 Detection of TSLP expression in bladder by RT-PCR. 

Wild type: only one band at 168 bp with primers F1/R1 (mTslp);

Homozygous: only one band at 160 bp with primers F2/R2 (hTSLP); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hTSLP and mTSLP expression in thymus homogenate by ELISA (n=5). 

Abbr. HO, homozygous; WT, wild type.

Note. hTSLP and C57BL/6 mice were i.p. injected with LPS.


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