hCD24

品系全名

C57BL/6JSmo-Cd24atm1(hCD24)Smoc

目录号

NM-HU-2000060

品系状态

胚胎冻存

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基因信息

基因名
CD24a

品系描述

通过同源重组,将小鼠基因CD24a进行人源化修饰。与此相似的品系还有hCD24(2)(NM-HU-215025),详细信息请咨询技术顾问。
应用领域:免疫治疗;药物筛选

验证数据

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Fig1. Detection of CD24 expression in spleen and brain by RT-PCR. Wild type: only one band at 175 bp with primers F1/R1(mCd24);Homozygous: only one band at 202 bp with primers F2/R2(hCD24); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Detection of hCD24 expression on B cells and T cells in blood in hCD24 KI mice.

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Fig3. Detection of hCD24 expression on macrophages, neutrophils and DCs in blood in hCD24 KI mice.

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Fig4. Detection of hCD24 expression on B cells and T cells in spleen in hCD24 KI mice.

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Fig5. Detection of hCD24 expression on macrophages, neutrophils and DCs in spleen in hCD24 KI mice.

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Fig6. Detection of hCD24 expression on RBC (red blood cells)  in hCD24 KI mice.


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