hCD40(BALB/c)

品系全名

BALB/cJSmo-Cd40tm1(hCD40)/Smoc

目录号

NM-HU-2000047

品系状态

胚胎冻存

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基因信息

基因名
CD40

品系描述

通过同源重组,将小鼠Cd40基因进行人源化修饰。
应用领域:免疫治疗;药物筛选

验证数据

图1.流式检测CD40人源化小鼠外周血中hCD40的表达水平。结果显示hCD40(BALB/c)人源化小鼠外周血B细胞中可以检测到hCD40的表达。

2.png

图2.流式检测CD40人源化小鼠脾脏B细胞中hCD40的表达水平。结果显示hCD40(BALB/c)人源化小鼠脾脏B细胞中可以检测到hCD40的表达。

image.png

图3. 流式检测CD40人源化小鼠脾脏DC细胞和巨噬细胞中hCD40的表达情况。结果显示,CD40人源化纯合子小鼠脾脏DC细胞和巨噬细胞中均可检测到hCD40的表达。(数据由冠科提供)



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