hSIGLEC8(2)

品系全名

C57BL/6JSmo-Siglecftm1(hSIGLEC8)Smoc

目录号

NM-HU-210033

品系状态

胚胎冻存

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基因信息

基因名
Siglecf

品系描述

通过同源重组,将小鼠基因Siglecf进行人源化修饰。与此相似的品系还有hSIGLEC8(NM-HU-204983),详细信息请咨询技术顾问。
应用领域:免疫治疗;药物筛选

验证数据

1.png

图1. 流式检测SIGLEC8人源化小鼠脾脏中hSIGLEC8的表达情况。结果显示SIGLEC8人源化纯合子小鼠脾脏中可以检测到hSIGLEC8的表达。

2.png

图2. 流式检测SIGLEC8人源化小鼠PBMC中hSIGLEC8的表达情况。结果显示SIGLEC8人源化纯合子小鼠PBMC中可以检测到hSIGLEC8的表达。



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