hIL9

品系全名

C57BL/6JSmo-Il9tm3(hIL9)Smoc

目录号

NM-HU-18029

品系状态

活体

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基因信息

基因名
Il9

品系描述

通过同源重组,将小鼠Il9基因进行人源化修饰。
应用领域:免疫治疗;肿瘤研究;药物筛选

验证数据

IL9-HU.png

图1 Elisa检测IL9人源化纯合子(HO)小鼠中人源IL9的表达。IL-9-HU小鼠使用LPS刺激7h后,摘眼球取血清进行Elisa检测,结果显示IL9人源化纯合子小鼠中人源IL9表达活跃,符合预期。

IL9-MU.png

图2 Elisa检测IL9人源化纯合子(HO)小鼠中鼠源IL9的表达。使用LPS刺激7h后,摘眼球取血清进行Elisa检测,结果显示WT小鼠鼠源IL9表达活跃,HO小鼠无鼠源IL9表达,符合预期。


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