hPVRIG

品系全名

C57BL/6JSmo-Pvrigtm1(hPVRIG)/Smoc

目录号

NM-HU-210008

品系状态

活体

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基因信息

基因名
Pvrig

品系描述

通过同源重组,将小鼠基因Pvrig进行人源化修饰。与此相似的品系还有hPVRIG(2)(NM-HU-215013),详细信息请咨询技术顾问。
应用领域:药物筛选

验证数据

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Fig1. Detection of PVRIG expression in spleen by RT-PCR. 

Wild type: only one band at 291 bp with primers F1/R1(mPvrig); Homozygous: only one band at 351 bp with primers F2/R2(hPVRIG); Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig2. Detection of hPVRIG expression in Daudi cells.

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Fig3. Detection of hPVRIG expression in Spleen in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

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Fig4. Detection of hPVRIG expression in Blood in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.


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