hHER3(2)

品系全名

C57BL/6JSmo-Erbb3tm2(hERBB3)Smoc

目录号

NM-HU-225068

品系状态

胚胎冻存

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基因信息

基因名
Erbb3

品系描述

利用同源重组,将小鼠Erbb3基因进行人源化修饰。

验证数据

image.png

Fig.1 Detection of ERBB3 expression in colon by RT-PCR. 

Wild type: only one band at 343 bp with primers F1/R1(mErbb3);

Homozygous: only one band at 305 bp with primers F2/R2(hERBB3).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human hHER3 expression in hHER3(2) knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, homozygous; PC, positive control, MC38-hHER3 cells.

Note. The anti-human hHER3 antibody cross-reacted with mouse hHER3 and humanized hHER3. 


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