hSOST(2)

品系全名

C57BL/6JSmo-Sosttm2(hSOST)Smoc

目录号

NM-HU-215021

品系状态

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基因信息

基因名
Sost

品系描述

通过同源重组,将小鼠基因Sost进行人源化修饰。与此相似的品系还有hSOST(NM-HU-200251),详细信息请咨询技术顾问。
应用领域:硬化症1和颅骨干发育不良,常染色体显性

验证数据

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Fig1. Detection of SOST expression in testis and heart by RT-PCR. Wild type: only one band at 195 bp with primers F1/R1(mSost); Heterozygous: one band at 195 bp with primers F1/R1(mSost) and one band at 138 bp with primers F2/R2(hSOST); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig 2. Detection of hSOST expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.


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