hCD55

品系全名

C57BL/6JSmo-Cd55tm(hCD55)Smoc

目录号

NM-HU-215008

品系状态

胚胎冻存

导出PDF

基因信息

基因名
Meltf

品系描述

利用同源重组,将小鼠Cd55基因进行人源化修饰。
应用领域:补体过度激活、血管病血栓形成和蛋白质丢失的肠病和血型,克罗莫系统

验证数据

image.png

Fig1. Detection of CD55 expression in bladder by RT-PCR. 

Wild type: only one band at 310 bp with primers F1/R1(mCd55);

Homozygous: only one band at 304 bp with primers F2/R2(hCD55).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.image.png

Fig2. Detection of hCD55 expression in spleen in hCD55 KI mice.

image.png

Fig3. Detection of hCD55 expression in blood in hCD55 KI mice.


你也可能感兴趣

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

查看

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

查看

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

查看