hGDF15

品系全名

C57BL/6JSmo-Gdf15tm(hGDF15)Smoc

目录号

NM-HU-215002

品系状态

精子冻存

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基因信息

基因名
Faah

品系描述

利用同源重组,将小鼠Gdf15进行人源化修饰。
应用领域:心脏病和先天性贫血性贫血

验证数据

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Fig1. Detection of GDF15 expression inintestiner and colon and liver  by RT-PCR. Wild type: only one band at 314 bp with primers F1/R1(mGdf15);Homozygous: only one band at 160 bp with primers F2/R2(hGDF15); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig 2. Detection of hGDF15 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig 3. Detection of mGDF15 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.


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