Ifng-Venus-Luc
品系全名
C57BL/6JSmo-Ifngem1(IRES-Venus-Luci)Smoc
目录号
NM-KI-18041
品系状态
活体
基因信息
基因名
Ifng
品系描述
验证数据

图1. Ifng-Venus-Luci 报告小鼠移植MC38-OVA肿瘤细胞后的肿瘤生长曲线。红色箭头代表给药组给予PD1抑制剂治疗的时间点。

图2. Ifng-Venus-Luci小鼠MC38-OVA荷瘤模型活体成像验证。给药组(PD1抑制剂治疗组) IFNγ表达的荧光信号在第八天(第一次给药48小时后)时相较对照组有明显增强。随着药物发挥治疗效果,肿瘤逐渐变小,荧光信号也相应变小。
本数据由南模生物与Crownbio合作完成。
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