hCXCR3

品系全名

C57BL/6Smoc-Cxcr3tm1(hCXCR3)Smoc

目录号

NM-HU-200219

品系状态

胚胎冻存

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基因信息

基因名
Cxcr3

品系描述

利用CRISPR基因编辑技术,将小鼠Cxcr3基因全部或者部分替换为人源CXCR3,从而表达人或人鼠嵌合CXCR3蛋白,取代小鼠内源Cxcr3蛋白的表达。
应用领域:免疫相关;药物筛选

验证数据

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Fig 1. Detection of hCXCR3 expression on T cells in peripheral blood in WT C57BL/6 and HO hCXCR3 KI mice.

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Fig 2. Detection of hCXCR3 expression on T cells in spleen in WT C57BL/6 and HO hCXCR3 KI mice.


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