hIL20

品系全名

C57BL/6JSmo-Il20tm1(hIL20)Smoc

目录号

NM-HU-241679

品系状态

胚胎冻存

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基因信息

基因名
Il20

品系描述

利用同源重组,将小鼠Il20基因进行人源化修饰。

验证数据

image.png

Fig.1 Detection of IL20 expression in subcutaneous fat pad by RT-PCR (male, 14-week-old). 

Wild type: only one band at 122 bp with primers F1/R1(mIl20);

Homozygous: only one band at 130 bp with primers F2/R2(hIL20).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human IL20 expression in serum by ELISA (n=3, male, 14-week-old, Mean±SEM). 

Abbr.  HO, homozygous; WT, wild type.

Note. hIL20 and C57BL/6 mice were i.p. injected with LPS for 6h.


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