hC5(3)

品系全名

C57BL/6Smoc-Hcem1(hC5)Smoc

目录号

NM-HU-241686

品系状态

活体

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基因信息

基因名
Hc

品系描述

利用同源重组,将小鼠Hc基因进行人源化修饰。

验证数据

image.png

Fig.1 Detection of C5 expression in liver by RT-PCR. 

Wild type: only one band at 206 bp with primers F1/R1(mHc);

Homozygous: only one band at 165 bp with primers F2/R2(hC5).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human C5(A) and mouse C5(B) expression in serum by ELISA (n=3, female, 6-week-old). 

Abbr.  HO, homozygous; WT, wild type; N.D. not detected.


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