HLA-A24.2/B2M(2)
品系全名
C57BL/6Smoc-B2mem1(hB2M-linker-HLA-A*2402/H2-D1)Smoc
目录号
NM-HU-241352
品系状态
活体
基因信息
基因名
B2M
品系描述
验证数据
Fig.1 Expression analysis of hB2M(A) and HLA-ABC(B) on CD45+ cells in blood of HLA-A24.2/B2M humanized mice.
Leukocytes were collected from wild-type C57BL/6 mice(11 weeks old) and homozygous HLA-A11.1/B2M humanized mice(13.4 weeks old) , and analyzed by flow cytometry with anti-mB2M, anti-hB2M, anti-mH2D and anti-HLA-ABC. hB2M and HLA-ABC were exclusively detectable in HLA-A24.2/B2M humanized mice, whereas mB2M and mH2D were exclusively detectable in wild-type C57BL/6 mice.
Fig.2 Detection of immune cell subpopulations in the blood of male mice by FACS (n=3 in all groups, 13 weeks).
Abbr. WT, wild type; HO, homozygous.
Fig.3 Detection of immune cell subpopulations in the blood of female mice by FACS (n=3 in all groups, 13 weeks).
Abbr. WT, wild type; HO, homozygous.
Fig.4 Detection of immune cell subpopulations in the spleen of male mice by FACS (n=3 in all groups, 13 weeks).
Abbr. WT, wild type; HO, homozygous.
Fig.5 Detection of immune cell subpopulations in the spleen of female mice by FACS (n=3 in all groups, 13 weeks).
Abbr. WT, wild type; HO, homozygous.
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