hANGPTL3(5)
品系全名
C57BL/6Smoc-Angptl3tm2(hANGPTL3)Smoc
目录号
NM-HU-230047
品系状态
活体
基因信息
基因名
Angptl3
品系描述
利用同源重组，将小鼠Angptl3 基因进行人源化修饰。
*使用本品系发表的文献需注明: hANGPTL3(5) mice (Cat. NO. NM-HU-230047) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of ANGPTL3 expression in liver of HO hANGPTL3(5) mice by RT-PCR. （male， 8wks）
Wild type: only one band at 155 bp with primers F1/R1(mAngptl3);
Homozygous: only one band at 155 bp with primers F2/R2(hANGPTL3).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human ANGPTL3 expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type; N.D. not detected.
Table.1 Blood biochemical test of WT mice and hANGPTL3(5) knockin mice.
Values are expressed as mean±SEM.
Abbr. HO, homozygous; WT, wild type.
你也可能感兴趣
Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
查看
