Cartpt-IRES-Cre

品系全名

C57BL/6Smoc-Cartptem1(IRES-iCre)Smoc

目录号

NM-KI-200094

品系状态

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基因信息

基因名
Cartpt

品系描述

将IRES-iCre插入到小鼠Cartpt基因终止密码子处。
应用领域:Cre工具鼠,CART前体表达的细胞等区域

验证数据

Cartpt-IRES-iCre-1.png

Figure 1: Cartpt iCre/+; Rosa26tdTomato/+ 小鼠脑部tdTomato表达情况。

CartptiCre/+; Rosa26tdTomato/+ 双转基因鼠,可在皮质、脑核、下丘脑和中脑中表达tdTomato。证明Cartpt-(iCre)小鼠可以成为实现CART阳性细胞特异性敲除或表达的工具鼠。

Cartpt-IRES-iCre-2.png

Figure 2: CartptiCre/+; Rosa26tdTomato/+ 小鼠各组织中tdTomato的表达情况。




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